Small RNA sorting: matchmaking for Argonautes
Small RNAs directly or indirectly impact nearly every biological process in eukaryotic cells.
To perform their myriad roles, not only must precise small RNA species be generated, but …
To perform their myriad roles, not only must precise small RNA species be generated, but …
RNA interference in fungi: pathways, functions, and applications
Small RNA molecules of about 20 to 30 nucleotides function in gene regulation and
genomic defense via conserved eukaryotic RNA interference (RNAi)-related pathways. The …
genomic defense via conserved eukaryotic RNA interference (RNAi)-related pathways. The …
[HTML][HTML] C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts
HC Lee, W Gu, M Shirayama, E Youngman, D Conte… - Cell, 2012 - cell.com
Summary Piwi Argonautes and Piwi-interacting RNAs (piRNAs) mediate genome defense
by targeting transposons. However, many piRNA species lack obvious sequence …
by targeting transposons. However, many piRNA species lack obvious sequence …
Transgenerational inheritance of an acquired small RNA-based antiviral response in C. elegans
Induced expression of the Flock House virus in the soma of C. elegans results in the RNAi-
dependent production of virus-derived, small-interfering RNAs (viRNAs), which in turn …
dependent production of virus-derived, small-interfering RNAs (viRNAs), which in turn …
Argonaute proteins at a glance
C Ender, G Meister - Journal of cell science, 2010 - journals.biologists.com
1820 processing and unwinding steps, one strand of the dsRNA intermediate is
incorporated into an Argonaute-protein-containing complex that is referred to as an miRNA …
incorporated into an Argonaute-protein-containing complex that is referred to as an miRNA …
A tunable mechanism determines the duration of the transgenerational small RNA inheritance in C. elegans
In C. elegans, small RNAs enable transmission of epigenetic responses across multiple
generations. While RNAi inheritance mechanisms that enable" memorization" of ancestral …
generations. While RNAi inheritance mechanisms that enable" memorization" of ancestral …
[HTML][HTML] Endogenous RNAi pathways in C. elegans
In addition to several hundred microRNAs, C. elegans produces thousands of other small
RNAs targeting coding genes, pseudogenes, transposons, and other noncoding RNAs …
RNAs targeting coding genes, pseudogenes, transposons, and other noncoding RNAs …
Small RNAs in epigenetic inheritance: from mechanisms to trait transmission
G Cecere - FEBS letters, 2021 - Wiley Online Library
Inherited information is transmitted to progeny primarily by the genome through the gametes.
However, in recent years, epigenetic inheritance has been demonstrated in several …
However, in recent years, epigenetic inheritance has been demonstrated in several …
The Slicer Activity of ARGONAUTE1 Is Required Specifically for the Phasing, Not Production, of Trans-Acting Short Interfering RNAs in Arabidopsis
L Arribas-Hernández, A Marchais, C Poulsen… - The Plant …, 2016 - academic.oup.com
Abstract ARGONAUTE1 (AGO1) mediates posttranscriptional silencing by microRNAs
(miRNAs) and short interfering RNAS (siRNAs). AGO1-catalyzed RNA cleavage (slicing) …
(miRNAs) and short interfering RNAS (siRNAs). AGO1-catalyzed RNA cleavage (slicing) …
A neuronal piRNA pathway inhibits axon regeneration in C. elegans
Summary The PIWI-interacting RNA (piRNA) pathway has long been thought to function
solely in the germline, but evidence for its functions in somatic cells is emerging. Here we …
solely in the germline, but evidence for its functions in somatic cells is emerging. Here we …