Immune effector mechanisms in malaria
K Marsh, S Kinyanjui - Parasite immunology, 2006 - Wiley Online Library
That humans in endemic areas become immune to malaria offers encouragement to the
idea of developing protective vaccines. However natural immunity is relatively inefficient …
idea of developing protective vaccines. However natural immunity is relatively inefficient …
The IgH locus 3′ regulatory region: pulling the strings from behind
E Pinaud, M Marquet, R Fiancette, S Péron… - Advances in …, 2011 - Elsevier
Antigen receptor gene loci are among the most complex in mammals. The IgH locus,
encoding the immunoglobulin heavy chain (IgH) in B-lineage cells, undergoes major …
encoding the immunoglobulin heavy chain (IgH) in B-lineage cells, undergoes major …
Immunoglobulin G Subclass-Specific Responses against Plasmodium falciparum Merozoite Antigens Are Associated with Control of Parasitemia and Protection from …
DI Stanisic, JS Richards, FJ McCallum… - Infection and …, 2009 - Am Soc Microbiol
Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens
play a role in protection from malaria, although the precise targets and mechanisms …
play a role in protection from malaria, although the precise targets and mechanisms …
Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and …
DI Stanisic, FJI Fowkes, M Koinari, S Javati… - Infection and …, 2015 - Am Soc Microbiol
Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after
repeated exposure. Knowledge of the acquisition and nature of protective immune …
repeated exposure. Knowledge of the acquisition and nature of protective immune …
Duration of Naturally Acquired Antibody Responses to Blood-Stage Plasmodium falciparum Is Age Dependent and Antigen Specific
OJ Akpogheneta, NO Duah, KKA Tetteh… - Infection and …, 2008 - Am Soc Microbiol
Naturally acquired antibody responses provide partial protection from clinical malaria, and
blood-stage parasite vaccines under development aim to prime such responses. To …
blood-stage parasite vaccines under development aim to prime such responses. To …
Association between protection against clinical malaria and antibodies to merozoite surface antigens in an area of hyperendemicity in Myanmar: complementarity …
S Soe, M Theisen, C Roussilhon, KS Aye… - Infection and …, 2004 - Am Soc Microbiol
We performed a longitudinal clinical and parasitological follow-up study in OoDo, a village in
southeast Asia in which malaria is hyperendemic, in order to assess the association …
southeast Asia in which malaria is hyperendemic, in order to assess the association …
Target antigen, age, and duration of antigen exposure independently regulate immunoglobulin G subclass switching in malaria
JE Tongren, CJ Drakeley, SLR McDonald… - Infection and …, 2006 - Am Soc Microbiol
The isotype/subclass of immunoglobulin determines antibody function, but rather little is
known about factors that direct class switching in vivo. To evaluate factors that might …
known about factors that direct class switching in vivo. To evaluate factors that might …
Serum IgG3 to the Plasmodium falciparum merozoite surface protein 2 is strongly associated with a reduced prospective risk of malaria
WG Metzger, DMN Okenu, DR Cavanagh… - Parasite …, 2003 - Wiley Online Library
The merozoite surface protein 2 (MSP2) of Plasmodium falciparum is recognized by human
antibodies elicited during natural infections, and may be a target of protective immunity. In …
antibodies elicited during natural infections, and may be a target of protective immunity. In …
Antibodies to the Conserved C-Terminal Domain of the Plasmodium falciparum Merozoite Surface Protein 1 and to the Merozoite Extract and Their Relationship with …
R Perraut, L Marrama, B Diouf, C Sokhna… - Journal of Infectious …, 2005 - academic.oup.com
Antibodies to Plasmodium falciparum C-terminal merozoite surface protein 1 (PfMSP-1p19)
have been correlated with protection against malaria, but this association may apply to many …
have been correlated with protection against malaria, but this association may apply to many …
Antibodies to the N-Terminal Block 2 of Plasmodium falciparum Merozoite Surface Protein 1 Are Associated with Protection against Clinical Malaria
DR Cavanagh, D Dodoo, L Hviid… - Infection and …, 2004 - Am Soc Microbiol
This longitudinal prospective study shows that antibodies to the N-terminal block 2 region of
the Plasmodium falciparum merozoite surface protein 1 (MSP-1) are associated with …
the Plasmodium falciparum merozoite surface protein 1 (MSP-1) are associated with …