Rlip76: an unexplored player in neurodegeneration and Alzheimer's disease?

A Hindle, SP Singh, JA Pradeepkiran, C Bose… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the most
common cause of dementia in older people. AD is associated with the loss of synapses …

The subgroup of 2′-hydroxy-flavonoids: Molecular diversity, mechanism of action, and anticancer properties

C Bailly - Bioorganic & Medicinal Chemistry, 2021 - Elsevier
Flavonoids are abundant in nature, structurally very diversified and largely investigated.
However, the subgroup of 2′-hydroxyflavonoids is much less known and not frequently …

Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing

YC Chen, CY Chen, TW Chiang, MH Chan… - Nucleic acids …, 2023 - academic.oup.com
Abstract Trans-spliced RNAs (ts-RNAs) are a type of non-co-linear (NCL) transcripts that
consist of exons in an order topologically inconsistent with the corresponding DNA template …

Rlip76 in Ageing and Alzheimer's Disease: Focus on Oxidative Stress and Mitochondrial Mechanisms

M Bandaru, OF Sultana, MA Islam, A Rainier… - Ageing Research …, 2024 - Elsevier
Abstract RLIP76 (Rlip), a stress-responsive protein, plays a multifaceted role in cellular
function. This protein acts primarily as a glutathione-electrophile conjugate (GS-E) …

Anticancer activity of Ω-6 fatty acids through increased 4-hne in breast cancer cells

C Bose, A Hindle, J Lee, J Kopel, S Tonk, PT Palade… - Cancers, 2021 - mdpi.com
Simple Summary Epidemiological evidence suggests that breast cancer risk is lowered by Ω-
3 and increased by Ω-6 polyunsaturated fatty acids (PUFAs). Paradoxically, the Ω-6 PUFA …

Systematic identification and analysis of immune-related circRNAs of Pelteobagrus fulvidraco involved in Aeromonas veronii infection

Y He, L Ma, X Zeng, J Xie, X Ning - … and Physiology Part D: Genomics and …, 2024 - Elsevier
Circular RNA (circRNA) represents a type of newly discovered non-coding RNA,
distinguished by its closed loop structure formed through covalent bonds. Recent studies …

Haploinsufficiency interactions between RALBP1 and p53 in ERBB2 and PyVT models of mouse mammary carcinogenesis

SP Singh, J Lee, C Bose, H Li, YC Yuan, A Hindle… - Cancers, 2021 - mdpi.com
Simple Summary Rlip knockout has been reported to prevent cancer in highly cancer-
susceptible mice lacking p53, and Rlip knockdown kills many types of cancer cells. In …

Rlip Depletion Alters Oncogene Transcription at Multiple Distinct Regulatory Levels

A Hindle, C Bose, J Lee, PT Palade, CJ Peterson… - Cancers, 2022 - mdpi.com
Simple Summary Rlip76 is a multifunctional membrane protein that facilitates cancer growth,
and its depletion kills cancer cells. We recently found that Rlip depletion also results in …

Haploinsufficiency Interactions of RALBP1 and TP53 in Carcinogenesis

S Awasthi - Cancers, 2021 - mdpi.com
Mutagenic environmental chemical or radiant stresses directly damage DNA and amplify the
formation of potent endogenous mutagens from lipid peroxidation, leading to cancers that …

[PDF][PDF] Haploinsufficiency Interactions of RALBP1 and TP53 in Carcinogenesis. Cancers 2021, 13, 255

S Awasthi - 2021 - scienceopen.com
Mutagenic environmental chemical or radiant stresses directly damage DNA and amplify the
formation of potent endogenous mutagens from lipid peroxidation, leading to cancers that …