The therapeutic targeting of extracellular proteins is becoming hugely attractive in light of
evidence implicating the tumour microenvironment as pivotal in all aspects of tumour …

Exfoliation syndrome (XFS) is a common age-related disorder that leads to deposition of
extracellular fibrillar material throughout the body. The most recognized disease …

Glaucoma, a leading cause of blindness worldwide, is characterized by progressive optic
nerve damage, usually associated with intraocular pressure. Although the clinical …

Glaucoma, a progressive degenerative condition that results in the death of retinal ganglion
cells, is one of the leading causes of blindness, affecting millions worldwide. The …

Exfoliation syndrome (XFS) is the most common recognizable cause of open-angle
glaucoma worldwide. To better understand the etiology of XFS, we conducted a genome …

Pseudoexfoliation (PEX) syndrome is a generalized disease of the extracellular matrix and a
major cause of severe open-angle glaucoma. Single nucleotide polymorphisms (SNPs) in …

Pseudoexfoliation (PEX) syndrome is a generalized disease of the extracellular matrix and
the most common identifiable cause of open-angle glaucoma. Two single nucleotide …

Exfoliation syndrome is an age-related disease characterized by the production and
progressive accumulation of a fibrillar extracellular material in many ocular tissues. It leads …

Pseudoexfoliation (PEX) syndrome, one of the most common causes of glaucoma,
represents a complex, multifactorial, late-onset disease of worldwide significance. The …

Purpose To investigate whether variants in the lysyl oxidase-like 1 (LOXL1) gene are
associated with exfoliation glaucoma (XFG) and primary open-angle glaucoma (POAG) in …