Increased contractility and calcium sensitivity in cardiac myocytes isolated from endurance trained rats

U Wisløff, JP Loennechen, G Falck… - Cardiovascular …, 2001 - academic.oup.com
Objective: Regular exercise enhances cardiac function and modulates myocyte growth in
healthy individuals. The purpose of the present study was to assess contractile function and …

Mechanisms of exercise‐induced improvements in the contractile apparatus of the mammalian myocardium

OJ Kemi, U Wisløff - Acta physiologica, 2010 - Wiley Online Library
One of the main outcomes of aerobic endurance exercise training is the improved maximal
oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise …

Intensity-controlled treadmill running in rats: V˙o 2 max and cardiac hypertrophy

U Wisløff, J Helgerud, OJ Kemi… - American journal of …, 2001 - journals.physiology.org
Physiological studies of long-term cardiovascular adaptation to exercise require training
regimens that give robust conditioning effects and adequate testing procedures to quantify …

Intensity-controlled treadmill running in mice: cardiac and skeletal muscle hypertrophy

OJ Kemi, JP Loennechen, U Wisløff… - Journal of applied …, 2002 - journals.physiology.org
Whereas novel pathways of pathological heart enlargement have been unveiled by thoracic
aorta constriction in genetically modified mice, the molecular mechanisms of adaptive …

Loss of exercise-induced cardioprotection after cessation of exercise

SL Lennon, J Quindry, KL Hamilton… - Journal of applied …, 2004 - journals.physiology.org
Endurance exercise provides cardioprotection against ischemia-reperfusion (I/R) injury.
Exercise-induced cardioprotection is associated with increases in cytoprotective proteins …

Different regional effects of voluntary exercise on the mechanical and electrical properties of rat ventricular myocytes

AJ Natali, LA Wilson, M Peckham… - The Journal of …, 2002 - Wiley Online Library
Short‐term (6 weeks) voluntary wheel running exercise in young female rats that were in an
active growth phase resulted in whole‐heart hypertrophy and myocyte concentric …

Resistance training regulates cardiac function through modulation of miRNA-214

SFS Melo, VG Barauna, MAC Júnior, LHM Bozi… - International Journal of …, 2015 - mdpi.com
Aims: To determine the effects of resistance training (RT) on the expression of microRNA
(miRNA)-214 and its target in sarcoplasmic reticulum Ca2+-ATPase (SERCA2a), and on the …

Regional effects of voluntary exercise on cell size and contraction-frequency responses in rat cardiac myocytes

AJ Natali, DL Turner, SM Harrison… - Journal of …, 2001 - journals.biologists.com
ABSTRACT A model of voluntary exercise, in which rats are given free access to a running
wheel over a 14-week period, led to left ventricular hypertrophy. To test whether the …

[PDF][PDF] Exercise-induced changes in calcium handling in left ventricular cardiomyocytes

OJ Kemi, O Ellingsen, GL Smith, U Wisloff - Front Biosci, 2008 - article.imrpress.com
Introduction 3. Cardiomyocyte excitation-contraction coupling and calcium cycling 3.1.
Intracellular calcium and cardiomyocyte contractility 3.2. Calcium induces the myofilament …

Elevated MnSOD is not required for exercise-induced cardioprotection against myocardial stunning

SL Lennon, JC Quindry, KL Hamilton… - American Journal …, 2004 - journals.physiology.org
Endurance exercise provides cardioprotection against ischemia-reperfusion-induced
myocardial stunning and infarction. A recent study demonstrates that an exercise-induced …