Craniopharyngiomas (CPs) are slow growing, histologically benign intracranial tumors
located in the sellar–suprasellar region. Although known to have low mortality, their location …

Purpose The current knowledge on biological effects associated with proton therapy is
limited. Therefore, we investigated the distributions of dose, dose-averaged linear energy …

We investigate uncertainty guidance mechanisms to support proton therapy (PT) planning
visualization. Uncertainties in the PT workflow pose significant challenges for navigating …

Background Adamantinoma craniopharyngioma (ACP) is a non-malignant tumour of
unknown pathogenesis that frequently occurs in children and has malignant potential. The …

Purpose We quantified the effect of various forward‐based treatment‐planning strategies in
proton therapy on dose‐weighted linear energy transfer (LETd). By maintaining the …

Proton therapy offers a reduction in dose to normal tissue compared to conventional photon-
based radiotherapy. This is of particular benefit for pediatric patients as the majority are …

The fixed relative biological effectiveness (RBE) of 1.1 remains a controversial topic in
proton therapy. Clinicians have been reluctant to override this value. A method is proposed …

This is a comment on" Comments on" Temporal lobe sparing radiotherapy with photons or
protons for cognitive function preservation in paediatric craniopharyngioma" by Toussaint, et …

Abstract Background and Purpose Radiotherapy for paediatric posterior fossa tumours may
cause complications in the brainstem and upper spinal cord due to high doses. With proton …