Generic acquisition protocol for quantitative MRI of the spinal cord

J Cohen-Adad, E Alonso-Ortiz, M Abramovic… - Nature protocols, 2021 - nature.com
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Spinal cord atrophy in multiple sclerosis: a systematic review and meta‐analysis

C Casserly, EE Seyman, P Alcaide‐Leon… - Journal of …, 2018 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Spinal cord atrophy (SCA) is an important
emerging outcome measure in multiple sclerosis (MS); however, there is limited consensus …

Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks

C Gros, B De Leener, A Badji, J Maranzano, D Eden… - Neuroimage, 2019 - Elsevier
The spinal cord is frequently affected by atrophy and/or lesions in multiple sclerosis (MS)
patients. Segmentation of the spinal cord and lesions from MRI data provides measures of …

Radiologically isolated syndrome: 5-year risk for an initial clinical event

DT Okuda, A Siva, O Kantarci, M Inglese, I Katz… - PloS one, 2014 - journals.plos.org
Objective To report the 5-year risk and to identify risk factors for the development of a
seminal acute or progressive clinical event in a multi-national cohort of asymptomatic …

Advances in spinal cord imaging in multiple sclerosis

M Moccia, S Ruggieri, A Ianniello… - Therapeutic …, 2019 - journals.sagepub.com
The spinal cord is frequently affected in multiple sclerosis (MS), causing motor, sensory and
autonomic dysfunction. A number of pathological abnormalities, including demyelination …

Relevance of spinal cord abnormalities to clinical disability in multiple sclerosis: MR imaging findings in a large cohort of patients

C Lukas, MH Sombekke, B Bellenberg, HK Hahn… - Radiology, 2013 - pubs.rsna.org
Purpose To determine whether spinal cord atrophy differs among disease subtypes in
multiple sclerosis (MS) and whether it offers diagnostic and clinical correlative information …

MRI monitoring of pathological changes in the spinal cord in patients with multiple sclerosis

A Gass, MA Rocca, F Agosta, O Ciccarelli… - The Lancet …, 2015 - thelancet.com
The spinal cord is a clinically important site that is affected by pathological changes in most
patients with multiple sclerosis; however, imaging of the spinal cord with conventional MRI …

Reduced neurite density in the brain and cervical spinal cord in relapsing–remitting multiple sclerosis: A NODDI study

S Collorone, N Cawley, F Grussu… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: Multiple sclerosis (MS) affects both brain and spinal cord. However, studies of
the neuraxis with advanced magnetic resonance imaging (MRI) are rare because of long …

Association of HLA genetic risk burden with disease phenotypes in multiple sclerosis

N Isobe, A Keshavan, PA Gourraud, AH Zhu… - JAMA …, 2016 - jamanetwork.com
Importance Although multiple HLA alleles associated with multiple sclerosis (MS) risk have
been identified, genotype-phenotype studies in the HLA region remain scarce and …

Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration

H Kearney, MA Rocca, P Valsasina… - Multiple Sclerosis …, 2014 - journals.sagepub.com
Background: Understanding long-term disability in multiple sclerosis (MS) is a key goal of
research; it is relevant to how we monitor and treat the disease. Objectives: The Magnetic …