Brucellosis is a worldwide zoonosis affecting animal and human health. In the last several
decades, much research has been performed to develop safer Brucella vaccines to control …

There is currently no licensed vaccine for brucellosis in humans. Available animal vaccines
may cause disease and are considered unsuitable for use in humans. However, the …

Brucellosis is a worldwide zoonosis affecting animal and human health. Till now, there is no
effective vaccine licensed for brucellosis in humans. Although M5, H38 and 45/20 vaccines …

DNA vaccination has been of great interest since its discovery in the 1990s due to its ability
to elicit both humoral and cellular immune responses. DNA vaccines consist of a DNA …

Recently, advances in pharmaceutical research is focused on new delivery systems utilizing
new devices to achieve modification of delivery time, targeting, as well as improve the in vivo …

Brucella infections mainly occur through mucosal surfaces. Thus, the development of
mucosal administered vaccines could be instrumental for the control of brucellosis. Here, we …

Brucellosis is a group of closely associated zoonotic bacterial illnesses caused by members
of the genus Brucella. B. melitensis Omp31 is a promising candidate for a subunit vaccine …

In this review, we discuss recent developments in multicompartment systems commonly
referred to as vesosomes, as well as their method of preparation, surface modifications, and …

Background/Objectives In spite of all the research effort for developing new vaccines against
brucellosis, it remains unclear whether these new vaccine technologies will in fact become …

Brucellosis is an important zoonotic disease of nearly worldwide distribution. This pathogen
causes abortion in domestic animals and undulant fever, arthritis, endocarditis and …