Cytochrome P450 BM3 monooxygenase is the topic of extensive research as many
researchers have evolved this enzyme to generate a variety of products. However, the …

Enzymes that depend on sophisticated electron transfer via ferredoxins (Fds) exhibit
outstanding catalytic capabilities, but despite decades of research, many of them are still not …

Cytochrome P450s are versatile catalysts for biosynthesis applications. In the P450 catalytic
cycle, two electrons are required to reduce the heme iron and activate the subsequent …

The properties of natural products can be significantly influenced by glycosylation,
emphasizing the key role of glycosyltransferases (GTs) in this process. The pursuit of …

Many scientific fields, although driven by similar purposes and dealing with similar
technologies, often appear so isolated and far from each other that even the vocabularies to …

The P450 monooxygenase TleB (CYP107E48) catalyzes intramolecular C–S bond
formation in a thiol-containing substrate, yielding two sulfur-containing indolactam …

Daidzein is a major isoflavone compound with an immense pharmaceutical value. This
study applied a novel P450 CYP82D26 which can biosynthesize daidzein from (2 S) …

Cytochrome P450s are heme-containing enzymes capable of the oxidative transformation of
a wide range of organic substrates. A protein scaffold that coordinates the heme iron, and …

Covering: 2016 to the end of 2024 This highlight article aims to provide a perspective on the
challenges that novel biotechnological processes face in the biomanufacturing of natural …

Enzyme engineering aims to improve or install a new function in biocatalysts for applications
ranging from chemical synthesis to biomedicine. For decades, computational techniques …