Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges

S Bloch, KM Holleran, TL Kash, EM Vazey, JA Rinker… - Alcohol, 2022 - Elsevier
Alcohol use disorder (AUD) is frequently comorbid with mood disorders, and these co-
occurring neuropsychiatric disorders contribute to the development and maintenance of …

GABAergic implications in anxiety and related disorders

I Arora, P Mal, P Arora, A Paul, M Kumar - Biochemical and Biophysical …, 2024 - Elsevier
Evidence indicates that anxiety disorders arise from an imbalance in the functioning of brain
circuits that govern the modulation of emotional responses to possibly threatening stimuli …

Soybean isoflavones prevent atrazine-induced neurodegenerative damage by inducing autophagy

P Li, X Li, L Yao, Y Wu, B Li - Ecotoxicology and environmental safety, 2020 - Elsevier
Atrazine (ATR) is a widely used herbicide with documented dopaminergic (DAergic)
neurotoxicity that can lead to a Parkinson's disease (PD)-like motor syndrome. However …

Daidzein, but not genistein, has anxiolytic-liked effect on intact male Wistar rats

S Kalandakanond-Thongsong, S Daendee… - Behavioural Brain …, 2024 - Elsevier
The phytoestrogens daidzein and genistein are ubiquitous in human food. This study aimed
to elucidate their anxiety-liked effects, their effects on the reproductive organs, and the …

Peripubertal exposure of atrazine cause decrease in exploratory activity, deficits in sociability and few alterations on brain monoaminergic systems of rats

EL Ricci, J Zaccarelli-Magalhães, LP Pantaleon… - Toxicology and Applied …, 2024 - Elsevier
Atrazine is a pesticide used to control weeds in both in pre-and post-emergence crops. The
chronic exposure to atrazine can lead to severe damage in animals, especially in the …

Depletion of dietary phytoestrogens reduces hippocampal plasticity and contextual fear memory stability in adult male mouse

G Çalışkan, SA Raza, YE Demiray, E Kul… - Nutritional …, 2021 - Taylor & Francis
Introduction: Phytoestrogens are non-steroidal estrogen analogues and are found primarily
in soy products. They have received increasing attention as dietary supplements for …

Dietary phytoestrogens recalibrate socioemotional behavior in C57Bl/6J mice in a sex-and timing-dependent manner

CE Le Roux, AL Farthing, EK Lucas - Hormones and Behavior, 2025 - Elsevier
Estrogens are potent regulators of socioemotional behavior across species. Ubiquitous in
human and animal diets, plant-derived phytoestrogens (PE) bind estrogen receptors. While …

Postpartum depression in rats causes poor maternal care and neurochemical alterations on dams and long-lasting impairment in sociability on the offspring

J Zaccarelli-Magalhães, GR Abreu… - Behavioural brain …, 2023 - Elsevier
Postpartum depression is a mentally disabling disease with multifactorial etiology that affects
women worldwide. It can also influence child development and lead to behavioral and …

Prenatal Valproic Acid Induces Autistic‐Like Behaviors in Rats via Dopaminergic Modulation in Nigrostriatal and Mesocorticolimbic Pathways

LC Cezar, CCN da Fonseca, MO Klein… - Journal of …, 2025 - Wiley Online Library
Autism spectrum disorder (ASD) is a complex developmental disorder characterized by
several behavioral impairments, especially in socialization, communication, and the …

Preventive and therapeutic effects of genistein and daidzein on anxiety-like behaviors in ovariectomized rats

S Kalandakanond-Thongsong, S Daendee… - Neuroscience …, 2025 - Elsevier
Estrogen has demonstrated beneficial effects; however, it can also have unfavorable effects.
Phytoestrogens are present in many consumable products and commonly used as …