Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …

Solid tumours comprise many different cell types organized in spatially structured
arrangements, with substantial intratumour and intertumour heterogeneity. Advances in …

Our limited understanding of metabolic aging poses major challenges to comprehending the
diverse cellular alterations that contribute to age-related decline, and to devising targeted …

The rapid development of spatially resolved transcriptomics (SRT) technologies has
provided unprecedented opportunities for exploring the structure of specific organs or …

Melanoma, a malignant skin cancer arising from melanocytes, exhibits rapid metastasis and
a high mortality rate, especially in advanced stages. Current treatment modalities, including …

The androgen receptor (AR) signalling pathway has been intensively studied in the context
of prostate cancer, where androgen deprivation therapy is part of the standard of care for …

Spatial transcriptomics (ST technology allows for the detection of cellular transcriptome
information while preserving the spatial location of cells. This capability enables researchers …

Intracerebral hemorrhage (ICH) is a severe stroke subtype with limited therapeutic options.
Programmed cell death (PCD) is crucial for immunological balance, and includes …

Creative designs, precise fluidic manipulation, and automation have supported the
development of microfluidics for single-cell applications. Together with the advancements in …

Cancer immunotherapy, which leverages immune system components to treat malignancies,
has emerged as a cornerstone of contemporary therapeutic strategies. Yet, critical concerns …