Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

Cardiac fibrosis is a common pathophysiologic companion of most myocardial diseases,
and is associated with systolic and diastolic dysfunction, arrhythmogenesis, and adverse …

Making a firm diagnosis of chronic heart failure with preserved ejection fraction (HFpEF)
remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA–PEFF …

The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …

Heart failure (HF) is marked by distinctive changes in myocardial uptake and utilization of
energy substrates. Among the different types of HF, HF with preserved ejection fraction …

Background Enhanced inflammation may lead to exercise intolerance in heart failure with
preserved ejection fraction. The aim of the current study was to determine whether IL …

Heart failure with preserved ejection fraction (HFpEF) is caused, or exacerbated by, a wide
range of extracardiac conditions. Diabetes, obesity, and metabolic dysfunction are …

Atherosclerosis is a multifactorial chronic inflammatory arterial disease forming the
pathological basis of many cardiovascular diseases such as coronary heart disease, heart …

Over the last several decades, clinicians and clinical scientists have had growing interest in
heart failure (HF) diagnosis and treatment. While HF with reduced ejection fraction (EF) is a …

Abstract Context Prader-Willi syndrome (PWS) is a complex hypothalamic disorder,
combining hyperphagia, hypotonia, intellectual disability, and pituitary hormone …