Bioactive compounds: a goldmine for defining new strategies against pathogenic bacterial biofilms?

A Pompilio, M Scocchi, ML Mangoni… - Critical reviews in …, 2023 - Taylor & Francis
Most human infectious diseases are caused by microorganisms growing as biofilms. These
three-dimensional self-organized communities are embedded in a dense matrix allowing …

Biosynthesis of uridine diphosphate N‐Acetylglucosamine: An underexploited pathway in the search for novel antibiotics?

JA Wyllie, MV McKay, AS Barrow… - IUBMB …, 2022 - Wiley Online Library
Although the prevalence of antibiotic resistance is increasing at an alarming rate, there are a
dwindling number of effective antibiotics available. Thus, the development of novel …

Biogenic Synthesis, Characterization and Antibacterial Potential Evaluation of Copper Oxide Nanoparticles Against Escherichia coli

M Ali, M Ijaz, M Ikram, A Ul-Hamid, M Avais… - Nanoscale Research …, 2021 - Springer
The development of resistance against antibiotics used to treat bacterial infections along
with the prevalence of medication residues presents significant public health problems …

Polyketides in Aspergillus terreus: biosynthesis pathway discovery and application

Y Yin, M Cai, X Zhou, Z Li, Y Zhang - Applied microbiology and …, 2016 - Springer
The knowledge of biosynthesis gene clusters, production improving methods, and bioactivity
mechanisms is very important for the development of filamentous fungi metabolites …

Microbial bioactive compounds from oleaginous yeast culture: insights into molecular docking interactions and toxicity prediction

I Ayadi, S Akermi, M Louati, A Gargouri… - Biomass Conversion …, 2024 - Springer
Red yeasts, particularly from the Rhodotorula genus, have garnered significant interest as
valuable sources of metabolites with diverse natural biological activities. Their exceptional …

6-MSA, a secondary metabolite distribution hub with multiple fungal destinations

M Bejenari, TE Sondergaard… - Journal of Applied …, 2023 - academic.oup.com
methylsalicylic acid (6-MSA) is a small, simple polyketide produced by a broad spectrum of
fungal species. Since fungi obtained the ability to synthesize 6-MSA from bacteria through a …

Fungal metabolites for the control of biofilm infections

AB Estrela, WR Abraham - Agriculture, 2016 - mdpi.com
Many microbes attach to surfaces and produce a complex matrix of polymers surrounding
their cells, forming a biofilm. In biofilms, microbes are much better protected against hostile …

Insights into the biodegradation of pentachlorobiphenyl by Microbacterium paraoxydans: proteomic and metabolomic studies

L Ji, X Chang, L Wang, X Fu, W Lai, L Zheng… - Frontiers in …, 2024 - frontiersin.org
Bacterial degradation mechanism for high chlorinated pentachlorobiphenyl (PentaCB) with
worse biodegradability has not been fully elucidated, which could limit the full remediation of …

Antibacterial agents targeting the bacterial cell wall

L Shan, Q Wenling, P Mauro… - Current Medicinal …, 2020 - ingentaconnect.com
The introduction of antibiotics to treat bacterial infections either by killing or blocking their
growth has been accompanied by the studies of mechanism that allows the drugs to kill the …

[HTML][HTML] The bifunctional protein GlmU is a key factor in biofilm formation induced by alkylating stress in Mycobacterium smegmatis

A Di Somma, M Caterino, V Soni, M Agarwal… - Research in …, 2019 - Elsevier
Living organisms have developed specific defence mechanisms to counteract hostile
environmental conditions. Alkylation stress response mechanisms also occur in …