Application of porphyrins in antibacterial photodynamic therapy

BM Amos-Tautua, SP Songca, OS Oluwafemi - Molecules, 2019 - mdpi.com
Antibiotics are commonly used to control, treat, or prevent bacterial infections, however
bacterial resistance to all known classes of traditional antibiotics has greatly increased in the …

[HTML][HTML] Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

M Warszyńska, P Repetowski, JM Dąbrowski - Coordination Chemistry …, 2023 - Elsevier
Innovative anticancer therapies based on the activation of the immune system offer promise
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …

Engineering of relevant photodynamic processes through structural modifications of metallotetrapyrrolic photosensitizers

JM Dąbrowski, B Pucelik, A Regiel-Futyra… - Coordination Chemistry …, 2016 - Elsevier
Applications of metalloporphyrins and related molecules have been extensively pursued in
the context of photodynamic therapy of cancer (PDT) and other biomedical applications. This …

Hybrid materials for heterogeneous photocatalytic degradation of antibiotics

MJF Calvete, G Piccirillo, CS Vinagreiro… - Coordination Chemistry …, 2019 - Elsevier
The ever-growing number of multi-resistant bacteria caused by the proliferation of antibiotics
in the environment led to an increased interest in finding more sustainable processes for …

Recent advances in strategies for overcoming hypoxia in photodynamic therapy of cancer

B Pucelik, A Sułek, A Barzowska, JM Dąbrowski - Cancer Letters, 2020 - Elsevier
The selectivity of photodynamic therapy (PDT) derived from the tailored accumulation of
photosensitizing drug (photosensitizer; PS) in the tumor microenvironment (TME), and from …

Metalloporphyrins: bioinspired oxidation catalysts

MM Pereira, LD Dias, MJF Calvete - Acs Catalysis, 2018 - ACS Publications
The utilization of metalloporphyrins as bioinspired oxidation catalysts is an evolving topic of
research. By understanding the cytochrome P-450 mechanism of action, chemists have …

Reactive oxygen species in photodynamic therapy: mechanisms of their generation and potentiation

JM Dąbrowski - Advances in inorganic chemistry, 2017 - Elsevier
Reactive oxygen species (ROS) play key roles in cell signaling systems and homeostasis,
and they are also fundamental to photodynamic therapy (PDT). PDT efficacy can be affected …

[HTML][HTML] Bacteriochlorins and their metal complexes as NIR-absorbing photosensitizers: Properties, mechanisms, and applications

B Pucelik, A Sułek, JM Dąbrowski - Coordination Chemistry Reviews, 2020 - Elsevier
Bacterichlorins possess a characteristic intense electronic absorption in the near-infrared
part of the electromagnetic radiation (NIR) from 700 nm up to 900 nm, where endogenous …

Photodynamic inactivation of bacteria with porphyrin derivatives: effect of charge, lipophilicity, ROS generation, and cellular uptake on their biological activity in vitro

A Sułek, B Pucelik, M Kobielusz, A Barzowska… - International Journal of …, 2020 - mdpi.com
Resistance of microorganisms to antibiotics has led to research on various therapeutic
strategies with different mechanisms of action, including photodynamic inactivation (PDI). In …

Photodynamic inactivation (PDI) as a promising alternative to current pharmaceuticals for the treatment of resistant microorganisms

B Pucelik, JM Dąbrowski - Advances in inorganic Chemistry, 2022 - Elsevier
Although the whole world is currently observing the global battle against COVID-19, it
should not be underestimated that in the next 30 years, approximately 10 million people per …