Abstract Bone Morphogenetic Proteins (BMPs) are a group of signaling molecules that
belongs to the Transforming Growth Factor-β (TGF-β) superfamily of proteins. Initially …

Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in
regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited …

Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting
from knockouts of these genes in mice have provided tremendous insight into gene function …

The lack of therapies for progressive multiple sclerosis highlights the need to understand the
regenerative process of remyelination that can follow CNS demyelination. This involves an …

Mesenchymal stem cells (MSCs) can differentiate into several lineages during development
and also contribute to tissue homeostasis and regeneration, although the requirements for …

Bone morphogenetic proteins (BMPs) exhibit broad spectra of biological activities in various
tissues, including bone, cartilage, blood vessels, heart, kidney, neurons, liver and lung …

Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming
growth factor-β family of ligands. BMPs exhibit widespread utility and pleiotropic, context …

I. Introduction IN THE adult ovary, folliculogenesis starts when follicles leave the pool of
resting follicles (RF) to enter the growth phase. From there, the early growing follicle …

Since their original discovery as regulators of follicle-stimulating hormone (FSH) secretion
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …

GROWTH factors synthesized by ovarian somatic cells directly affect oocyte growth and
function1–6, but it is unclear whether oocyte-secreted factors6–9 play a reciprocal role in …