Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient
physiology and psychology. The microenvironment of the injured spinal cord is complicated …

The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary
mechanisms of injury. Though both mechanisms are involved in the neurological …

It has been previously reported that Nigella sativa oil (NSO) and thymoquinone (TQ), active
constituent of N. sativa seeds oil, may prevent oxidative injury in various models. Therefore …

Traumatic spinal cord injury (SCI) induces various complex pathological processes that
cause physical impairment and psychological devastation. The two phases of SCI are …

Neurologic trauma, encompassing traumatic brain injury (TBI) and acute spinal cord injury
(SCI), is a cause of significant morbidity and mortality in veterinary patients. In one recent …

Spinal cord injury (SCI) results in loss of function below the lesion. Secondary injury
following the primary impact includes a number of biochemical and cellular alterations …

Axonal degeneration occurs in multiple neurodegenerative disorders of the central and
peripheral nervous system. Although the underlying molecular pathways leading to axonal …

Numerous lines of evidence suggest that heterocyclic compounds used as analgesic, anti-
inflammatory and anti-migraine agents can be potent regulators of the nitroxidative stress …

Substantial knowledge has been gained in the pathological findings following naturally
occurring spinal cord injury (SCI) in dogs and cats. The molecular mechanisms involved in …

Multiple sclerosis (MS) is a CNS disease that includes demyelination and axonal
degeneration. Voltage-gated Na+ channels are abnormally expressed and distributed in MS …