Role of tunneling nanotubes in viral infection, neurodegenerative disease, and cancer
The network of tunneling nanotubes (TNTs) represents the filamentous (F)-actin rich tubular
structure which is connected to the cytoplasm of the adjacent and or distant cells to mediate …
structure which is connected to the cytoplasm of the adjacent and or distant cells to mediate …
HIV-1 and HTLV-1 transmission modes: Mechanisms and importance for virus spread
So far, only two retroviruses, human immunodeficiency virus (HIV)(type 1 and 2) and human
T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans …
T-cell lymphotropic virus type 1 (HTLV-1), have been recognized as pathogenic for humans …
Targeting lipid rafts—a potential therapy for COVID-19
COVID-19 is a global pandemic currently in an acute phase of rapid expansion. While public
health measures remain the most effective protection strategy at this stage, when the peak …
health measures remain the most effective protection strategy at this stage, when the peak …
Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells
MD Kolba, W Dudka, M Zaręba-Kozioł, A Kominek… - Cell death & …, 2019 - nature.com
Intercellular communication within the bone marrow niche significantly promotes
leukemogenesis and provides protection of leukemic cells from therapy. Secreted factors …
leukemogenesis and provides protection of leukemic cells from therapy. Secreted factors …
Bridging the gap: virus long-distance spread via tunneling nanotubes
RJJ Jansens, A Tishchenko, HW Favoreel - Journal of virology, 2020 - Am Soc Microbiol
Tunneling nanotubes (TNTs) are actin-based intercellular conduits that connect distant cells
and allow intercellular transfer of molecular information, including genetic information …
and allow intercellular transfer of molecular information, including genetic information …
HTLV-1 extracellular vesicles promote cell-to-cell contact
DO Pinto, C DeMarino, ML Pleet, M Cowen… - Frontiers in …, 2019 - frontiersin.org
Human T-cell leukemia virus-1 (HTLV-1) is a neglected and incurable retrovirus estimated to
infect 5 to 10 million worldwide. Specific indigenous Australian populations report infection …
infect 5 to 10 million worldwide. Specific indigenous Australian populations report infection …
HTLV-1 infection and pathogenesis: new insights from cellular and animal models
G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …
models have provided invaluable contributions in the knowledge of viral infection …
Lipid rafts and pathogens: the art of deception and exploitation: Thematic Review Series: Biology of Lipid Rafts
MI Bukrinsky, N Mukhamedova, D Sviridov - Journal of lipid research, 2020 - ASBMB
Lipid rafts, solid regions of the plasma membrane enriched in cholesterol and
glycosphingolipids, are essential parts of a cell. Functionally, lipid rafts present a platform …
glycosphingolipids, are essential parts of a cell. Functionally, lipid rafts present a platform …
NK cells and monocytes modulate primary HTLV-1 infection
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1
infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type …
infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type …
Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread
DO Pinto, S Al Sharif, G Mensah, M Cowen, P Khatkar… - Retrovirology, 2021 - Springer
Abstract Background The Human T-cell Lymphotropic Virus Type-1 (HTLV-1) is a blood-
borne pathogen and etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV …
borne pathogen and etiological agent of Adult T-cell Leukemia/Lymphoma (ATLL) and HTLV …