[HTML][HTML] Comparative digestive physiology

WH Karasov, AE Douglas - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
In vertebrates and invertebrates, morphological and functional features of gastrointestinal
(GI) tracts generally reflect food chemistry, such as content of carbohydrates, proteins, fats …

Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet

JP Lallès - Nutrition reviews, 2010 - academic.oup.com
The diverse nature of intestinal alkaline phosphatase (IAP) functions has remained elusive,
and it is only recently that four additional major functions of IAP have been revealed. The …

[图书][B] Mammalian alkaline phosphatases: from biology to applications in medicine and biotechnology

JL Millán - 2006 - books.google.com
A review and discussion of new knowledge on the structure and function of mammalian
alkaline phosphatases (APs) gained over the last 25 years. It covers:* The structure …

The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis

M Zarepour, K Bhullar, M Montero, C Ma… - Infection and …, 2013 - Am Soc Microbiol
Salmonella enterica serovar Typhimurium is a model organism used to explore the virulence
strategies underlying Salmonella pathogenesis. Although intestinal mucus is the first line of …

Multisystemic functions of alkaline phosphatases

R Buchet, JL Millán, D Magne - Phosphatase modulators, 2013 - Springer
Human and mouse alkaline phosphatases (AP) are encoded by a multigene family
expressed ubiquitously in multiple tissues. Gene knockout (KO) findings have helped define …

Clinical pathology

GD Bossart, TH Reidarson, LA Dierauf… - CRC handbook of …, 2001 - taylorfrancis.com
Over the past decade, an information explosion has occurred in the field of veterinary clinical
pathology. This is partially due to impressive technological advances in diagnostic …

Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide

H Bentala, WR Verweij, A Huizinga-Van der Vlag… - Shock, 2002 - journals.lww.com
Lipopolysaccharide (LPS) may cause sepsis when it enters the blood circulation. The toxic
moiety of LPS is the well-preserved lipid A part. Lipid A contains two phosphate groups …

Dephosphorylation of endotoxin by alkaline phosphatase in vivo.

K Poelstra, WW Bakker, PA Klok… - The American journal …, 1997 - ncbi.nlm.nih.gov
Natural substrates for alkaline phosphatase (AP) are at present not identified despite
extensive investigations. Difficulties in imagining a possible physiological function involve its …

Alkaline phosphatases reduce toxicity of lipopolysaccharides in vivo and in vitro through dephosphorylation

I Koyama, T Matsunaga, T Harada, S Hokari… - Clinical …, 2002 - Elsevier
Intestinal alkaline phosphatase (AP), as a host defense factor, was first investigated in vivo
using rats orally exposed to lipopolysaccharide (LPS). After the oral administration of LPS to …

Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification

EL Campbell, CF MacManus… - Proceedings of the …, 2010 - National Acad Sciences
Resolvin-E1 (RvE1) has been demonstrated to promote inflammatory resolution in
numerous disease models. Given the importance of epithelial cells to coordination of …