Hypospadias is the most common congenital anomaly of the penis. The problem usually
develops sporadically and without an obvious underlying cause. The ectopically positioned …

Surgical correction of hypospadias is proposed to improve the aesthetic and functional
quality of the penis. Hormone therapy preceding surgical correction is indicated to obtain …

Context: Isolated hypospadias may result from impaired testicular function or androgen end-
organ defects or, alternatively, from hormone-independent abnormalities of morphogenetic …

The hypospadiac genital tubercle (GT) is the consequence of a development arrest of the
tissues forming its ventral aspect, which occurs during the “masculinization window”(6–16 …

Introduction Hypospadias is the most common malformation of the penis. Despite the
common assumption that hypospadias may affect children's psychosexual development …

PURPOSE: Human chorionic gonadotropin (HCG) has a stimulatory effect on testicular
steroidogenesis and has been widely used for evaluating male Leydig cell function …

Introduction The use of preoperative hormonal stimulation before hypospadias surgery aims
to increase penile size and achieve better surgical results; however, the rules are not clear …

Studies over the last years show an increase in testicular cancer, hypospadias and
cryptorchidism in industrial countries, leading to the concept of testicular dysgenesis …

Fetal testicular androgens in several mammalian species are responsible for the sexual
differentiation of both the genitalia and the brain, the latter effect being related to behavioral …

What's known on the subject? and What does the study add? Despite diverse anatomical
and histological trials in humans and animal models, the aetiology of hypospadias remains …