The expanding complexity of estrogen receptor signaling in the cardiovascular system

S Menazza, E Murphy - Circulation research, 2016 - Am Heart Assoc
Estrogen has important effects on cardiovascular function including regulation of vascular
function, blood pressure, endothelial relaxation, and the development of hypertrophy and …

The effects of oestrogens and their receptors on cardiometabolic health

E Morselli, RS Santos, A Criollo, MD Nelson… - Nature Reviews …, 2017 - nature.com
Cardiovascular disease (CVD) is one of the leading causes of mortality in developed
countries. The incidence of CVD is sexually dimorphic, and research has focused on the …

Estrogens, estrogen receptors effects on cardiac and skeletal muscle mitochondria

R Ventura-Clapier, J Piquereau, V Veksler… - Frontiers in …, 2019 - frontiersin.org
Mitochondria are unique organelles present in almost all cell types. They are involved not
only in the supply of energy to the host cell, but also in multiple biochemical and biological …

The Role of 17β-Estradiol and Estrogen Receptors in Regulation of Ca2+ Channels and Mitochondrial Function in Cardiomyocytes

S Mahmoodzadeh, E Dworatzek - Frontiers in Endocrinology, 2019 - frontiersin.org
Numerous epidemiological, clinical, and animal studies showed that cardiac function and
manifestation of cardiovascular diseases (CVDs) are different between males and females …

The role of estrogen and estrogen receptors on cardiomyocytes: an overview

T Luo, JK Kim - Canadian Journal of Cardiology, 2016 - Elsevier
Sex differences in the onset and manifestation of cardiovascular diseases are well known,
yet the mechanism behind this discrepancy remains obscure. Estrogen and its …

Prevalence of cancer in Takotsubo cardiomyopathy: short and long-term outcome

K Sattler, I El-Battrawy, S Lang, X Zhou… - International journal of …, 2017 - Elsevier
Abstract Background Takotsubo Cardiomyopathy (TTC) is a transient disorder of ventricular
wall dysfunction, mostly induced by physical or emotional stress. TTC may be associated …

Non-genomic effects of estrogen on cell homeostasis and remodeling with special focus on cardiac ischemia/reperfusion injury

R Puglisi, G Mattia, A Carè, G Marano… - Frontiers in …, 2019 - frontiersin.org
This review takes into consideration the main mechanisms involved in cellular remodeling
following an ischemic injury, with special focus on the possible role played by non-genomic …

Sex differences, genetic and environmental influences on dilated cardiomyopathy

A Jain, N Norton, KA Bruno, LT Cooper Jr… - Journal of clinical …, 2021 - mdpi.com
Dilated cardiomyopathy (DCM) is characterized by dilatation of the left ventricle and
impaired systolic function and is the second most common cause of heart failure after …

Sex differences in cardiovascular diseases: a matter of estrogens, ceramides, and sphingosine 1-phosphate

B Arosio, G Corbi, S Davinelli, V Giordano… - International Journal of …, 2022 - mdpi.com
The medical community recognizes sex-related differences in pathophysiology and
cardiovascular disease outcomes (CVD), culminating with heart failure. In general, pre …

Systemic oxidative stress, aging and the risk of cardiovascular events in the general female population

MF Bourgonje, AR Bourgonje, AE Abdulle… - Frontiers in …, 2021 - frontiersin.org
Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative
stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free …