COVID-19, myocarditis and pericarditis

DL Fairweather, DJ Beetler, DN Di Florio… - Circulation …, 2023 - Am Heart Assoc
Viral infections are a leading cause of myocarditis and pericarditis worldwide, conditions that
frequently coexist. Myocarditis and pericarditis were some of the early comorbidities …

[HTML][HTML] Inflammation and Epstein–Barr Virus at the Crossroads of Multiple Sclerosis and Post-Acute Sequelae of COVID-19 Infection

BA Rousseau, S Bhaduri-McIntosh - Viruses, 2023 - mdpi.com
Recent studies have strengthened the evidence for Epstein–Barr Virus (EBV) as an
important contributing factor in the development of multiple sclerosis (MS). Chronic …

[HTML][HTML] Soluble P2X7 receptor is elevated in the plasma of COVID-19 patients and correlates with disease severity

J García-Villalba, L Hurtado-Navarro… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a tightly coordinated response against bacterial and viral infections,
triggered by the production of pro-inflammatory cytokines. SARS-CoV-2 infection induces …

Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19

YY Yong, L Zhang, YJ Hu, JM Wu, L Yan, YR Pan… - Clinical …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging evidence indicates that …

Tranilast as an adjunctive therapy in hospitalized patients with severe COVID-19: a randomized controlled trial

A Saeedi-Boroujeni, R Nashibi, AA Ghadiri… - Archives of medical …, 2022 - Elsevier
Background Tranilast is a potential NLRP3 inflammasome inhibitor that may relieve
progressive inflammation due to COVID-19. Aim of the study To evaluate the therapeutic …

[HTML][HTML] Luteolin-rich fraction from Perilla frutescens seed meal inhibits spike glycoprotein S1 of SARS-CoV-2-induced NLRP3 inflammasome lung cell inflammation …

S Dissook, S Umsumarng, S Mapoung… - Frontiers in …, 2023 - frontiersin.org
Objective The multi-systemic inflammation as a result of COVID-19 can persevere long after
the initial symptoms of the illness have subsided. These effects are referred to as Long …

Roles of mitochondrial DNA in dynamics of the immune response to COVID-19

A Mahmoodpoor, S Sanaie, Z Ostadi, M Eskandari… - Gene, 2022 - Elsevier
Mitochondria dynamics have a pivotal role in many aspects of immune function. Viral
infections affect mitochondrial dynamics and trigger the release of mitochondrial DNA …

The double sides of NLRP3 inflammasome activation in sepsis

C Vigneron, BF Py, G Monneret, F Venet - Clinical Science, 2023 - portlandpress.com
Sepsis is defined as a life-threatening organ dysfunction induced by a dysregulated host
immune response to infection. Immune response induced by sepsis is complex and …

[HTML][HTML] Immunosuppressant therapies in COVID-19: is the TNF axis an alternative?

Y Palacios, L Chavez-Galan - Pharmaceuticals, 2022 - mdpi.com
The study of cytokine storm in COVID-19 has been having different edges in accordance
with the knowledge of the disease. Various cytokines have been the focus, especially to …

[HTML][HTML] Immune damage mechanisms of COVID-19 and novel strategies in prevention and control of epidemic

Y Sun, B Luo, Y Liu, Y Wu, Y Chen - Frontiers in immunology, 2023 - frontiersin.org
Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coronavirus
disease 2019 (COVID-19) has diverse clinical manifestations, which is the main feature of …