Health effects research and regulation of diesel exhaust: an historical overview focused on lung cancer risk

TW Hesterberg, CM Long, WB Bunn, CA Lapin… - Inhalation …, 2012 - Taylor & Francis
The mutagenicity of organic solvent extracts from diesel exhaust particulate (DEP), first
noted more than 55 years ago, initiated an avalanche of diesel exhaust (DE) health effects …

Diesel engine exhaust: basis for occupational exposure limit value

P Taxell, T Santonen - Toxicological Sciences, 2017 - academic.oup.com
Diesel engines are widely used in transport and power supply, making occupational
exposure to diesel exhaust common. Both human and animal studies associate exposure to …

Phospholipid lung surfactant and nanoparticle surface toxicity: Lessons from diesel soots and silicate dusts

WE Wallace, MJ Keane, DK Murray… - … and occupational health, 2007 - Springer
Because of their small size, the specific surface areas of nanoparticulate materials (NP),
described as particles having at least one dimension smaller than 100 nm, can be large …

Micronucleus assays

WU Müller, C Streffer - Advances in mutagenesis research, 1994 - Springer
Small, round-shaped structures that stained like the cell nucleus were observed in the
cytoplasm of erythrocytes more than a century ago (Neumann 1869, p. 78; Howell 1891; for …

Health effects of subchronic exposure to environmental levels of diesel exhaust

MD Reed, AP Gigliotti, JD McDonald… - Inhalation …, 2004 - Taylor & Francis
Diesel exhaust is a public health concern and contributor to both ambient and occupational
air pollution. As part of a general health assessment of multiple anthropogenic source …

Case‐control study on occupational exposure to diesel exhaust and lung cancer risk

PB Md, RE Harris, EL Wynder - American journal of industrial …, 1990 - Wiley Online Library
The association between lung cancer and occupations with probable exposure to diesel
exhaust (DE) was studied among 2,584 cases and 5,099 hospital controls. The crudeodds …

Age and gender effects on genotoxicity in diesel exhaust particles exposed C57BL/6 mice

JW Lee, JS Kim, HJ Lee, JH Jang, JH Kim, WJ Sim… - Biomolecules, 2021 - mdpi.com
There is growing evidence that the accumulation of DNA damage induced by fine particulate
matter (PM2. 5) exposure is an underlying mechanism of pulmonary disease onset and …

Mutagenicity spectra in bacterial strains of airborne and engine exhaust particulate extracts

R Crebelli, S Fuselli, G Conti, L Conti… - Mutation Research/Genetic …, 1991 - Elsevier
The mutagenicity spectra of the organic extracts of both airborne particulate matter and
diesel and gasoline soot particles were determined using a battery of 9 bacterial strains of …

The effect of fuel composition on the mutagenicity of diesel engine exhaust

R Crebelli, L Conti, B Crochi, A Carera, C Bertoli… - Mutation Research …, 1995 - Elsevier
The effect of fuel composition on the mutagenicity of diesel engine emission was
investigated. To this end, a fuel matrix comprising fuels with different contents of aromatic …

Life-style and genetic factors that determine the susceptibility to the production of chromosome damage

K Morimoto - Chromosomal aberrations: Basic and applied aspects, 1990 - Springer
Chromosome alterations, which are directly visible changes in the DNA, have close
associations to cancer development (German 1973; Carins 1981; Klein 1981). Lymphocytes …