Gels as vaginal drug delivery systems

J Das Neves, MF Bahia - International journal of Pharmaceutics, 2006 - Elsevier
The vagina has been used as a mucosal drug delivery route for a long time. Its single
characteristics can be either limitative or advantageous when drug delivery is considered …

[图书][B] Enhancement in drug delivery

E Touitou, BW Barry - 2006 - taylorfrancis.com
Providing a significant cross-fertilization of ideas across several disciplines, Enhancement in
Drug Delivery offers a unique comprehensive review of both theoretical and practical …

Microemulsion based vaginal gel of fluconazole: formulation, in vitro and in vivo evaluation

YG Bachhav, VB Patravale - International Journal of Pharmaceutics, 2009 - Elsevier
The objective of the present investigation was to develop and evaluate microemulsion
based gel for the vaginal delivery of fluconazole (FLZ). The solubility of FLZ in oils and …

Development and characterization of chitosan nanoparticles loaded nanofiber hybrid system for vaginal controlled release of benzydamine

F Tuğcu-Demiröz, S Saar, AA Kara, A Yıldız… - European Journal of …, 2021 - Elsevier
Vaginal infections caused by various pathogens such as fungi, viruses and protozoa are
frequently seen. Systemic and local treatments can be applied to eliminate these infections …

pH-sensitive Eudragit nanoparticles for mucosal drug delivery

JW Yoo, N Giri, CH Lee - International journal of Pharmaceutics, 2011 - Elsevier
Drug delivery via vaginal epithelium has suffered from lack of stability due to acidic and
enzymatic environments. The biocompatible pH-sensitive nanoparticles composed of …

Liposomal drugs dispersed in hydrogels: effect of liposome, drug and gel properties on drug release kinetics

S Mourtas, S Fotopoulou, S Duraj, V Sfika… - Colloids and Surfaces B …, 2007 - Elsevier
Release of calcein and griseofulvin (GRF) from control (gels in which solutes are dissolved
in) and liposomal gels was studied using agarose-assisted immobilization as a technique to …

Development of long-acting bioadhesive vaginal gels of oxybutynin: Formulation, in vitro and in vivo evaluations

F Tuğcu-Demiröz, F Acartürk, D Erdoğan - International journal of …, 2013 - Elsevier
Overactive bladder (OAB) and vaginal dryness are common problems after menopause.
Oxybutynin (OXY) is an antimuscarinic agent that has been available for more than 30 years …

The physicodynamic properties of mucoadhesive polymeric films developed as female controlled drug delivery system

JW Yoo, K Dharmala, CH Lee - International journal of pharmaceutics, 2006 - Elsevier
To develop an efficient female controlled drug delivery system (FcDDS) against sexually
transmitted diseases (STDs), the polymeric films containing sodium dodecyl sulfate (SDS) …

Development of a novel synergistic thermosensitive gel for vaginal candidiasis: an in vitro, in vivo evaluation

MA Mirza, S Ahmad, MN Mallick, N Manzoor… - Colloids and Surfaces B …, 2013 - Elsevier
The singular aim of the proposed work is the development of a synergistic thermosensitive
gel for vaginal application in subjects prone to recurrent vaginal candidiasis and other …

[HTML][HTML] Surface tension in human pathophysiology and its application as a medical diagnostic tool

A Fathi-Azarbayjani, A Jouyban - BioImpacts: BI, 2015 - ncbi.nlm.nih.gov
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Introduction: Pathological features of disease appear to be quite different. Despite this …