Pharmaceutical approaches for enhancing solubility and oral bioavailability of poorly soluble drugs

I Nyamba, CB Sombie, M Yabre… - European Journal of …, 2024 - Elsevier
High solubility in water and physiological fluids is an indispensable requirement for the
pharmacological efficacy of an active pharmaceutical ingredient. Indeed, it is well …

[HTML][HTML] Bioactive compound encapsulation: Characteristics, applications in food systems, and implications for human health

A Rezagholizade-Shirvan, M Soltani, S Shokri… - Food chemistry: X, 2024 - Elsevier
Nanotechnology plays a pivotal role in food science, particularly in the nanoencapsulation of
bioactive compounds, to enhance their stability, bioavailability, and therapeutic potential …

Microencapsulation for pharmaceutical applications: a review

C Yan, SR Kim - ACS Applied Bio Materials, 2024 - ACS Publications
In order to improve bioavailability, stability, control release, and target delivery of active
pharmaceutical ingredients (APIs), as well as to mask their bitter taste, to increase their …

A novel baking additive: Preparation, characterization, and application of chitosan hydrochloride/carboxymethyl starch sodium nano-gel for wheat bread

X Dou, Y Hao, Y Sun, P Yang, L Liu, Y He, Y Shi… - Food …, 2024 - Elsevier
In this study, we hypothesized that chitosan hydrochloride/carboxymethyl starch sodium
(CHC-CMS-Na) nanogels could improve bread quality as a baking additive. Starch-based …

[HTML][HTML] Critical review of food colloidal delivery system for bioactive compounds: physical characterization and application

B Wang, J LvYe, S Yang, Y Shi, Q Chen - Foods, 2024 - mdpi.com
Bioactive compounds (BACs) have attracted much attention due to their potential health
benefits. However, such substances have problems such as difficulty dissolving in water …

[HTML][HTML] Sodium Alginate–Starch Capsules for Enhanced Stability of Metformin in Simulated Gastrointestinal Fluids

R Gheorghita, IO Sirbu, A Lobiuc, M Covasa - Biomimetics, 2024 - mdpi.com
The use of biopolymers in pharmaceuticals is well established, particularly for encapsulating
biologically active compounds due to their beneficial properties. Alginate, widely recognized …

Recent developments in encapsulation techniques for innovative and high-quality dairy products: Demands and challenges

SM El-Sayed, HS El-Sayed, AM Youssef - Bioactive Carbohydrates and …, 2024 - Elsevier
The dairy industry is experiencing significant technological and societal changes, resulting
in shifts in product availability and consumer preferences. Encapsulation technologies, such …

Synergizing additive manufacturing and machine learning for advanced hydroxyapatite scaffold design in bone regeneration

A Zarei, A Farazin - Journal of the Australian Ceramic Society, 2024 - Springer
Additive manufacturing (AM) methods have sparked interest within the tissue engineering
domain due to their adaptability and capacity to fabricate constructs featuring intricate …

Recent advances in delivery of transdermal nutrients: A review

L Fan, J Huang, S Ma - Experimental Dermatology, 2024 - Wiley Online Library
Nutrients provide vital functions in the body for sustained health, which have been shown to
be related to the incidence, prevention and treatment of disease. However, limited …

Hydrophobic Coating Platforms for High‐Efficiency Loading and Direct Transmembrane Delivery of Fat‐Soluble Osteogenic Drug for Enhanced Osseointegration of …

Y Chen, X Ning, X Jia, H Xin, S Kong… - Advanced Functional …, 2024 - Wiley Online Library
Compared with water‐soluble osteogenic drugs, fat‐soluble osteogenic drugs exhibit higher
bioavailability and drug stability, making them valuable for enhancing the osseointegration …