For centuries, itch was categorized as a submodality of pain. Recent research over the last
decade has led to the realization that itch is in fact a separate and distinct, albeit closely …

The discovery, in 2006, that loss-of-function mutations in the filaggrin (FLG) gene are the
cause of ichthyosis vulgaris—the most common disorder of keratinization—and also a strong …

Background Eczema is a common chronic skin condition. Probiotics have been proposed as
an effective treatment for eczema; their use is increasing, as numerous clinical trials are …

A genetic basis for atopic dermatitis (AD) has long been recognized. Historic documents
allude to family history of disease as a risk factor. Before characterization of the human …

Atopic dermatitis (AD) is a common chronic inflammatory skin disease that exhibits a
complex interplay of skin barrier disruption and immune dysregulation. Patients with AD are …

We have previously proposed that the pathogenesis of eosinophilic esophagitis (EE) is
mediated by an IL-13–driven epithelial cell response associated with marked gene …

Agriculture surplus were used as substrates to synthesize γ-aminobutyric acid (GABA) by
Lactobacillus plantarum DSM19463 for the manufacture of a functional beverage or as a …

Atopic eczema or dermatitis (AD) is a chronically relapsing dermatitis associated with
pruritus, sleep disturbance, psychosocial symptoms, and impaired quality of life. It affects 10 …

Multiple genetic as well as environmental factors interact in the pathogenesis of eczema.
Increased understanding of genetic predisposition in atopy and eczema has directed …

Atopic dermatitis (AD) in older adults represents a newly defined subgroup of AD. The
prevalence of elderly AD is approximately 1–3% among elderly populations in industrialized …