Post-translational modifications (PTMs) add a major degree of complexity to the proteome
and are essential controllers of protein homeostasis. Amongst the hundreds of PTMs …

Summary Ubiquitin-fold modifier 1 (UFM1) is a ubiquitin-like protein covalently conjugated
with intracellular proteins through UFMylation, a process similar to ubiquitylation. Growing …

UFMylation involves the covalent modification of substrate proteins with UFM1 (Ubiquitin‐
fold modifier 1) and is important for maintaining ER homeostasis. Stalled translation triggers …

Ufmylation is implicated in multiple cellular processes, but little is known about its functions
and regulation in protein trafficking. Here, we demonstrate that the genetic depletion of core …

The stabilization of stalled forks has emerged as a crucial mechanism driving resistance to
poly (ADP-ribose) polymerase (PARP) inhibitors in BRCA1/2-deficient tumors. Here, we …

Ubiquitin Fold Modifier‐1 (UFM1) is a ubiquitin‐like modifier (UBL) that is posttranslationally
attached to lysine residues on substrates via a dedicated system of enzymes conserved in …

CRISPR (clustered regularly interspaced short palindromic repeats) technology holds
tremendous promise for gene regulation and editing. However, precise control of CRISPR …

Ubiquitin-fold modifier 1 (UFM1) is a newly identified ubiquitin-like protein that has been
conserved during the evolution of multicellular organisms. In a similar manner to ubiquitin …

Post‐translational modification is a rite of passage for cellular functional proteins and
ultimately regulate almost all aspects of life. Ubiquitin‐fold modifier 1 (UFM1) system …

Abstract Double‐strand break (DSB), a significant DNA damage brought on by ionizing
radiation, acts as an initiating signal in tumor radiotherapy, causing cancer cells death. The …