Arabidopsis telomerase takes off by uncoupling enzyme activity from telomere length maintenance in space

BB Barcenilla, AD Meyers, C Castillo-González… - Nature …, 2023 - nature.com
Spaceflight-induced changes in astronaut telomeres have garnered significant attention in
recent years. While plants represent an essential component of future long-duration space …

Different mutational function of low‐and high‐linear energy transfer heavy‐ion irradiation demonstrated by whole‐genome resequencing of Arabidopsis mutants

Y Kazama, K Ishii, T Hirano, T Wakana… - The Plant …, 2017 - Wiley Online Library
Heavy‐ion irradiation is a powerful mutagen that possesses high linear energy transfer
(LET). Several studies have indicated that the value of LET affects DNA lesion formation in …

Exploring hypoxic biology to improve radiotherapy outcomes

C Li, L Wiseman, E Okoh, M Lind, R Roy… - Expert Reviews in …, 2022 - cambridge.org
Ionising radiotherapy is a well-established, effective cancer treatment modality, whose
efficacy has improved with the application of newer technological modalities. However …

Frequency and Spectrum of Mutations Induced by Gamma Rays Revealed by Phenotype Screening and Whole-Genome Re-Sequencing in Arabidopsis thaliana

Y Du, Z Feng, J Wang, W Jin, Z Wang, T Guo… - International Journal of …, 2022 - mdpi.com
Genetic variations are an important source of germplasm diversity, as it provides an allele
resource that contributes to the development of new traits for plant breeding. Gamma rays …

SUPPRESSOR OF GAMMA RESPONSE1 links DNA damage response to organ regeneration

RA Johnson, PA Conklin, M Tjahjadi… - Plant …, 2018 - academic.oup.com
In Arabidopsis, DNA damage-induced programmed cell death is limited to the meristematic
stem cell niche and its early descendants. The significance of this cell-type-specific …

Characterization of gamma irradiation-induced mutations in Arabidopsis mutants deficient in non-homologous end joining

Y Du, Y Hase, K Satoh… - Journal of Radiation …, 2020 - academic.oup.com
To investigate the involvement of the non-homologous end joining (NHEJ) pathway in plant
mutagenesis by ionizing radiation, we conducted a genome-wide characterization of the …

Radiation and radiation disorders

JA Jones, F Karouia, L Pinsky, O Cristea - Principles of Clinical Medicine …, 2019 - Springer
With current technologies, radiation doses associated with exploration and habitation
missions to the Moon and Mars may well exceed the limits currently defined for LEO …

Approaches for Surveying Cosmic Radiation Damage in Large Populations of Seeds–Antarctic Balloons and Particle Beams

B Califar, R Tucker, J Cromie, N Sng… - … and Space Research, 2020 - sciendo.com
ABSTRACT The Cosmic Ray Exposure Sequencing Science (CRESS) payload system was
a proof of concept experiment to assess the genomic impact of space radiation on seeds …

Secondary malignancies in the era of high-precision radiation therapy

EK Balcer-Kubiczek, JG Eley - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Although modern radiation therapy delivers a localized distribution of ionizing energy that
can be used to cure primary cancers for many patients, the inevitable radiation exposure to …

RNA Sequencing-Based Transcriptome Analysis in Response to Different Types and Doses of Ionizing Radiation in Rice

JW Park, J Kim - Plant breeding and biotechnology, 2021 - kiss.kstudy.com
Ionizing radiation (IR) is regarded as an abiotic stressor for plants because it causes
oxidative stress and changes the expression of genes. We investigated RNA sequencing …