Immunotoxicity of three environmental mycotoxins and their risks of increasing pathogen infections

Y Sun, Y Song, M Long, S Yang - Toxins, 2023 - mdpi.com
Aflatoxin B1 (AFB1), ochratoxin A (OTA), and deoxynivalenol (DON) are the three
mycotoxins that have received the most scholarly attention and have been tested most …

Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update

SP Rendic, FP Guengerich - Archives of toxicology, 2021 - Springer
This is an overview of the metabolic activation of drugs, natural products, physiological
compounds, and general chemicals by the catalytic activity of cytochrome P450 enzymes …

Risk assessment of aflatoxins in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
EFSA was asked to deliver a scientific opinion on the risks to public health related to the
presence of aflatoxins in food. The risk assessment was confined to aflatoxin B1 (AFB 1) …

Risk assessment of ochratoxin A in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA to update their 2006 opinion on ochratoxin
A (OTA) in food. OTA is produced by fungi of the genus Aspergillus and Penicillium and …

Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation

M Bauer, B Fink, L Thürmann, M Eszlinger… - Clinical …, 2016 - Springer
Background Tobacco smoke is worldwide one of the main preventable lifestyle inhalative
pollutants causing severe adverse health effects. Epidemiological studies revealed …

Neurotoxic effects of aflatoxin B1 on human astrocytes in vitro and on glial cell development in zebrafish in vivo

S Park, JY Lee, S You, G Song, W Lim - Journal of hazardous materials, 2020 - Elsevier
Aflatoxin B1 is one of the well-known mycotoxins and mainly found in contaminated animal
feed and various agricultural products inducing acute and chronic toxicology, tumor, and …

[HTML][HTML] Aryl hydrocarbon receptor is activated in patients and mice with chronic kidney disease

L Dou, S Poitevin, M Sallée, T Addi, B Gondouin… - Kidney international, 2018 - Elsevier
Patients with chronic kidney disease (CKD) are exposed to uremic toxins and have an
increased risk of cardiovascular disease. Some uremic toxins, like indoxyl sulfate, are …

Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism

H Li, JN Lampe - Archives of biochemistry and biophysics, 2019 - Elsevier
The human cytochrome P450 CYP3A7, once thought to be an enzyme exclusive to fetal
livers, has more recently been identified in neonates and developing infants as old as 24 …

Environmentally relevant level of aflatoxin B1 elicits toxic pro-inflammatory response in murine CNS-derived cells

J Mehrzad, AM Malvandi, M Alipour, S Hosseinkhani - Toxicology letters, 2017 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is a well-known member of aflatoxins (AFs) that is considered
among highly stable toxic contaminants of food, worldwide. The impact of AFB 1 on neural …

Hidden hazards revealed: Mycotoxins and their masked forms in poultry

H Okasha, B Song, Z Song - Toxins, 2024 - mdpi.com
The presence of mycotoxins and their masked forms in chicken feed poses a significant
threat to both productivity and health. This review examines the multifaceted impacts of …