Multimodal data fusion for cancer biomarker discovery with deep learning

S Steyaert, M Pizurica, D Nagaraj… - Nature machine …, 2023 - nature.com
Technological advances have made it possible to study a patient from multiple angles with
high-dimensional, high-throughput multiscale biomedical data. In oncology, massive …

Microbiome multi-omics network analysis: statistical considerations, limitations, and opportunities

D Jiang, CR Armour, C Hu, M Mei, C Tian… - Frontiers in …, 2019 - frontiersin.org
The advent of large-scale microbiome studies affords newfound analytical opportunities to
understand how these communities of microbes operate and relate to their environment …

Deep learning with multimodal representation for pancancer prognosis prediction

A Cheerla, O Gevaert - Bioinformatics, 2019 - academic.oup.com
Motivation Estimating the future course of patients with cancer lesions is invaluable to
physicians; however, current clinical methods fail to effectively use the vast amount of …

Evaluation and comparison of multi-omics data integration methods for cancer subtyping

R Duan, L Gao, Y Gao, Y Hu, H Xu… - PLoS computational …, 2021 - journals.plos.org
Computational integrative analysis has become a significant approach in the data-driven
exploration of biological problems. Many integration methods for cancer subtyping have …

Approaches to integrating metabolomics and multi-omics data: a primer

T Jendoubi - Metabolites, 2021 - mdpi.com
Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Modeling precision treatment of breast cancer

A Daemen, OL Griffith, LM Heiser, NJ Wang… - Genome biology, 2013 - Springer
Background First-generation molecular profiles for human breast cancers have enabled the
identification of features that can predict therapeutic response; however, little is known about …

Multi-omics integration—a comparison of unsupervised clustering methodologies

G Tini, L Marchetti, C Priami… - Briefings in …, 2019 - academic.oup.com
With the recent developments in the field of multi-omics integration, the interest in factors
such as data preprocessing, choice of the integration method and the number of different …

iBAG: integrative Bayesian analysis of high-dimensional multiplatform genomics data

W Wang, V Baladandayuthapani, JS Morris… - …, 2013 - academic.oup.com
Motivation: Analyzing data from multi-platform genomics experiments combined with
patients' clinical outcomes helps us understand the complex biological processes that …

Patient similarity: emerging concepts in systems and precision medicine

SA Brown - Frontiers in physiology, 2016 - frontiersin.org
Healthcare data generates a huge volume of information in various formats at high velocity
with sometimes questionable veracity (Barkhordari and Niamanesh, 2015)(4V). As a result …

Data integration of structured and unstructured sources for assigning clinical codes to patient stays

E Scheurwegs, K Luyckx, L Luyten… - Journal of the …, 2016 - academic.oup.com
Objective Enormous amounts of healthcare data are becoming increasingly accessible
through the large-scale adoption of electronic health records. In this work, structured and …