Hypoalbuminemia is associated with the acquisition and severity of infectious diseases, and
intact innate and adaptive immune responses depend on albumin. Albumin oxidation and …

Abstract The Working Party makes more than 100 tabulated recommendations in
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …

Medication-induced nephrotoxicity remains one of the most common causes of acute kidney
injury (AKI) among hospitalized patients. Within the extensive group of medications …

Purpose Colistin is an antibiotic that was introduced many years ago and was withdrawn
because of its nephrotoxicity. Nowadays, reemergence of this antibiotic for multi-drug …

Rates of antibiotic resistance in Pseudomonas aeruginosa are increasing worldwide. The
multidrug-resistant (MDR) phenotype in P. aeruginosa could be mediated by several …

Colistin is a polymyxin antibiotic that was discovered in the late 1940s for the treatment of
gram‐negative infections. After several years of clinical use, its popularity diminished …

Background Nephrotoxicity and neurotoxicity are commonly associated with polymyxin
treatment; however, the emergence of multidrug-resistant Gram-negative bacteria with …

Colistin has been re-introduced into clinical practice for the treatment of carbapenem-
resistant Gram-negative bacteria. Studies in the last decade attempted to reconstruct the …

Colistin is a complex polypeptide antibiotic composed mainly of colistin A and B. It was
abandoned from clinical use in the 1970s because of significant renal and, to a lesser …

The emergence of multidrug resistant (MDR) infections and the shortage of new therapeutic
options have made colistin, a polymyxin antibiotic, the main option for the treatment of MDR …