J Caers, L Garderet, KM Kortüm, ME O'Dwyer… - …, 2018 - ncbi.nlm.nih.gov
The diagnosis of multiple myeloma can be challenging, even for experienced physicians, and requires close collaboration between numerous disciplines (orthopedics, radiology …
Amplification of 1q21 occurs in approximately 30% of de novo and 70% of relapsed multiple myeloma (MM) and is correlated with disease progression and drug resistance. Here, we …
Abstract 1q21 amplification is an important prognostic marker in multiple myeloma. In this study we identified that IL6R (the interleukin-6 membrane receptor) and ADAR1 (an RNA …
L Gao, Y Liu, Y Li, L Feng, Z Wang, L Wen… - … Myeloma and Leukemia, 2022 - Elsevier
Background The cut-off value for gain/amplification of 1q21 (1q21+) was 20% according to the recommendations of the European Myeloma Network and there were limited studies …
Y Kazuma, K Shirakawa, Y Tashiro, H Yamazaki… - Scientific Reports, 2022 - nature.com
Abstract DNA cytosine deaminase APOBEC3B (A3B) is an endogenous source of mutations in many human cancers, including multiple myeloma. A3B proteins form catalytically inactive …
A Daudignon, W Cuccuini, C Bracquemart… - Current Research in …, 2023 - Elsevier
Multiple myeloma (MM) is characterized by the accumulation of malignant plasma cells (PCs) in the bone marrow. Despite considerable advances in the treatment, MM is …
A Daudignon, B Quilichini, G Ameye, H Poirel… - Annales de biologie …, 2016 - jle.com
[3] Dimopoulos M., Terpos E., Comenzo RL, Tosi P., Beksac M., Sezer O. International myeloma working group consensus statement and guidelines regarding the current role of …