Fusions of two genes can lead to the generation of chimeric RNAs, which may have a
distinct functional role from their original molecules. Chimeric RNAs could encode novel …

Viral infections can modulate the widespread alternations of cellular splicing, favouring viral
replication within the host cells by overcoming host immune responses. However, how …

The ongoing COVID-19 pandemic caused by SARS-CoV-2 infections has quickly developed
into a global public health threat. COVID-19 patients show distinct clinical features, and in …

Gene fusions and their chimeric products are commonly linked with cancer. However, recent
studies have found chimeric transcripts in non-cancer tissues and cell lines. Large-scale …

Abstract Background: Worldwide, approximately 1.7 billion people are afflicted with
musculoskeletal (MSK) diseases, posing significant health challenges. The introduction of …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation
and joint damage. Transcriptomics has been utilized in RA profiling to identify locations that …