Terpenoids from the medicinal mushroom Antrodia camphorata: Chemistry and medicinal potential

Y Kuang, B Li, Z Wang, X Qiao, M Ye - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to February 2020 Antrodia camphorata is a medicinal mushroom endemic to
Taiwan for the treatment of intoxication, liver injury, cancer, and inflammation. Owing to its …

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical …

JH Wong, TB Ng, HHL Chan, Q Liu, GCW Man… - Applied Microbiology …, 2020 - Springer
This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered
which are better known include the following: button mushroom Agaricus bisporus, Brazilian …

Bioluminescence imaging applications in cancer: A comprehensive review

N Alsawaftah, A Farooq, S Dhou… - IEEE reviews in …, 2020 - ieeexplore.ieee.org
Bioluminescence imaging (BLI), an optical preclinical imaging modality, is an invaluable
imaging modality due to its low-cost, high throughput, fast acquisition times, and functional …

Multiomics identification of potential targets for Alzheimer disease and antrocin as a therapeutic candidate

ATH Wu, B Lawal, L Wei, YT Wen, DTW Tzeng, WC Lo - Pharmaceutics, 2021 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of neurodegenerative dementia and
affects nearly 50 million people worldwide. Early stage diagnosis of AD is challenging, and …

The Biosynthetic Gene Cluster of Mushroom‐Derived Antrocin Encodes Two Dual‐Functional Haloacid Dehalogenase‐like Terpene Cyclases

TH Chen, CT Chen, CF Lee, RJ Huang… - Angewandte Chemie …, 2023 - Wiley Online Library
Antrocin (1), produced by the medicinal mushroom Antrodia cinnamomea, is a potent
antiproliferative compound. The biosynthetic gene cluster of 1 was identified, and the …

Sesquiterpene lactones as emerging biomolecules to cease cancer by targeting apoptosis

CY Hsu, S Rajabi, M Hamzeloo-Moghadam… - Frontiers in …, 2024 - frontiersin.org
Apoptosis is a programmed cell death comprising two signaling cascades including the
intrinsic and extrinsic pathways. This process has been shown to be involved in the therapy …

Ovatodiolide and antrocin synergistically inhibit the stemness and metastatic potential of hepatocellular carcinoma via impairing ribosome biogenesis and modulating …

MY Chen, CH Hsu, SA Setiawan, DTW Tzeng, HP Ma… - Phytomedicine, 2023 - Elsevier
Activation of mitogen-activated protein kinase (MAPK) and PI3K signaling confers resistance
against sorafenib, a mainstay treatment for advanced hepatocellular carcinoma (HCC) …

Natural and synthetic lactones possessing antitumor activities

Y Kim, S Sengupta, T Sim - International Journal of Molecular Sciences, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, accounting for an estimated 8 million
deaths each year. As a result, there have been urgent unmet medical needs to discover …

Transcriptomic discovery of a theranostic signature (SERPINE1/MMP3/COL1A1/SPP1) for head and neck squamous cell carcinomas and identification of antrocinol as …

ML Shih, JC Lee, SY Cheng, B Lawal, CL Ho… - Computers in Biology …, 2022 - Elsevier
Head and neck squamous cell carcinomas (HNSCC) are prevalent malignancies with a
disappointing prognosis, necessitating the search for theranostic biomarkers for better …

Large-scale transcriptomic analysis of coding and non-coding pathological biomarkers, associated with the tumor immune microenvironment of thyroid cancer and …

ML Shih, B Lawal, SY Cheng, JO Olugbodi… - Frontiers in cell and …, 2022 - frontiersin.org
Papillary thyroid carcinoma (PTC) is the most prevalent endocrine malignancy with a
steadily increasing global incidence in recent decades. The pathogenesis of PTC is poorly …