The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …

Tenomodulin (TNMD, Tnmd) is a gene highly expressed in tendon known to be important for
tendon maturation with key implications for the residing tendon stem/progenitor cells as well …

Tendon self-renewal is a rare occurrence because of the poor vascularization of this tissue;
therefore, reconstructive surgery using autologous tendon is often performed in severe injury …

Tendon and ligament (T/L) engineering is a growing area of research with potential to
address the inadequacies of current T/L defect treatments. Our group previously developed …

Mesenchymal stem cells (MSCs) are pluripotent cells that primarily differentiate into
osteocytes, chondrocytes and adipocytes. Recent studies indicate that MSCs can also be …

Rotator cuff (RTC) repair outcomes are unsatisfactory due to the poor healing capacity of the
tendon bone interface (TBI). In our preceding study, tendon hydrogel (tHG), which is a type I …

Introduction Multipotent progenitor populations exist within the tendon proper and peritenon
of the Achilles tendon. Progenitor populations derived from the tendon proper and peritenon …

A decline in the body's motor functions has been linked to decreased muscle mass and
function in the oral cavity and throat; however, aging of the junctions of the muscles and …

Purpose Tendons are difficult to heal owing to their hypocellularity and hypovascularity. Our
laboratory has developed a tendon-derived hydrogel (tHG) that significantly improves …

Human pluripotent stem cells (PSCs) are used as a platform for therapeutic purposes such
as cell transplantation therapy and drug discovery. Another motivation for studying PSCs is …