Infections are one of the most significant complications of neonates, especially those born
preterm, with sepsis as one of the principal causes of mortality. Coagulase-negative …

Neonatal Infections are among the most common reasons for admission to the intensive
care unit. Neonatal sepsis (NS) significantly contributes to mortality rates. Empiric antibiotic …

The limit for possible survival after extremely preterm birth has steadily improved and
consequently, more premature neonates with increasingly lower gestational age at birth now …

Background/Objectives: The combination of isoniazid (INH) and rifampicin (RIF) is indicated
for the treatment maintenance phase of tuberculosis (TB) in adults and children. In Brazil …

Vaccinations for coronavirus disease-2019 (COVID-19) have begun more than a year
before, yet without specific treatments available. Rifampicin, critically important for human …

Abstract Cytochrome P450 3A4 (CYP3A4) is a crucial enzyme involved in the Phase I
metabolism of numerous medications used in clinical practice. Its potential significance in …

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Objective Determine the associations between neonatal intensive care unit (NICU)
medication safety practices, laboratory-based adverse events (lab-AEs), and death. Study …

• Increasing evidence in animal and human models links antibiotic exposure with alterations
in the microbiome, the developing immune system, and subsequent effects on health.• …

Myelosuppression, a potential adverse reaction of nafcillin and rifampin, is rarely
documented in pediatric populations. The objective of this study is to describe the incidence …