Objective Data: Fat mass has been shown to increase in aging women; however, the extent
to which menopausal status mediates these changes remains unclear. The purpose of this …

Menopause nomenclature varies in the scholarly literature making synthesis and
interpretation of research findings difficult. Therefore, the present study aimed to review and …

Objective: To review recent advances in understanding the role of leptin in the physiology
and pathophysiology of reproduction, with a focus on relevant clinical situations. Design: A …

Sex steroid hormones are involved in the metabolism, accumulation and distribution of
adipose tissues. It is now known that oestrogen receptor, progesterone receptor and …

Leptin is a hormone with multiple biological actions which is produced predominantly by
adipose tissue; in humans, plasma levels correlate with total body fat, and particularly high …

Type 2 diabetes mellitus (T2DM) is among the leading causes of death in postmenopausal
women. The disruption of ovarian function may contribute to the incidence of T2DM. The …

Obesity and its related metabolic diseases have reached a pandemic level worldwide. There
are sex differences in the prevalence of obesity and its related metabolic diseases, with men …

Leptin regulates glucose, lipid and energy homeostasis as well as feeding behavior, serving
as a bridge between peripheral metabolically active tissues and the central nervous system …

The roles of leptin, nesfatin-1 and kisspeptin in the regulation of food intake and/or
reproduction are well known; however, the interactions between these hormones remain …

Objective The peak bone mass is recognized as an important determinant in the
development of osteoporosis. We investigated associations between bone mineral density …