Deep eutectic solvents for pharmaceutical formulation and drug delivery applications

S Emami, A Shayanfar - Pharmaceutical development and …, 2020 - Taylor & Francis
Solvents play key roles in designing drug delivery systems (DDSs). They are used as the
reaction media in the preparation of DDSs and as vehicles for delivery of problematic drugs …

[HTML][HTML] Chemical enhancer: a simplistic way to modulate barrier function of the stratum corneum

T Haque, MMU Talukder - Advanced pharmaceutical bulletin, 2018 - ncbi.nlm.nih.gov
Human skin could be a prime target to deliver drugs into the human body as it is the largest
organ of human body. However, the main challenge of delivering drug into the skin is the …

In vitro percutaneous absorption studies of cannabidiol using human skin: Exploring the effect of drug concentration, chemical enhancers, and essential oils

MSA Junaid, AO Tijani, A Puri, AK Banga - International journal of …, 2022 - Elsevier
Cannabidiol, a non-psychoactive constituent of cannabis, has garnered much attention after
United States Food and Drug Administration approved Epidiolex® for oral use. Although …

Topically applied therapies for the treatment of skin disease: past, present, and future

M Brown, A Williams, RP Chilcott, B Brady, J Lenn… - Pharmacological …, 2024 - Elsevier
The purpose of this review is to summarize essential biological, pharmaceutical, and clinical
aspects in the field of topically applied medicines that may help scientists when trying to …

Nanocrystals for improved dermal drug delivery

O Pelikh, PL Stahr, J Huang, M Gerst, P Scholz… - European Journal of …, 2018 - Elsevier
Nanocrystals are composed of 100% active and possess an increased aqueous solubility
and dissolution velocity when compared to larger sized materials. Nanocrystals can be used …

Lipid nanoparticles in topical dermal drug delivery: Does chemistry of lipid persuade skin penetration?

VGSS Jyothi, SM Ghouse, DK Khatri, S Nanduri… - Journal of Drug Delivery …, 2022 - Elsevier
Lipid nanostructures such as solid lipid nanoparticles (SLNs) and nanostructured lipid
carriers (NLCs) significantly fetched the attention of scientific fraternity owing to lucrative …

[HTML][HTML] Nanocrystals in Dermal Drug Delivery: A Breakthrough for Enhanced Skin Penetration and Targeted Skin Disorder Treatments

AS Alnaim - Pharmaceutics, 2024 - mdpi.com
One of the major challenges in dermal drug delivery is the adequate penetration of the
active compound into the skin without causing any skin irritation and inflammation …

Franz cell diffusion testing and quantitative confocal raman spectroscopy: In vitro-in vivo correlation

F Iliopoulos, PJ Caspers, GJ Puppels, ME Lane - Pharmaceutics, 2020 - mdpi.com
Previously, we reported the use of Confocal Raman Spectroscopy (CRS) to investigate the
topical delivery of actives and excipients. We have also correlated the results from CRS with …

State of the art in Stratum Corneum research: The biophysical properties of ceramides

T Schmitt, RHH Neubert - Chemistry and physics of lipids, 2018 - Elsevier
This review is summarizing an important part of the state of the art in stratum corneum
research. A complete overview on discoveries about the general biophysical and …

Estradiol-loaded PLGA nanoparticles for improving low bone mineral density of cancellous bone caused by osteoporosis: Application of enhanced charged …

I Takeuchi, S Kobayashi, Y Hida, K Makino - Colloids and Surfaces B …, 2017 - Elsevier
Postmenopausal osteoporosis among older women, which occurs by an ovarian hormone
deficiency, is one of the major public health problems. 17 β-estradiol (E2) is used to prevent …