Illuminating the brain: advances and perspectives in optoelectronics for neural activity monitoring and modulation

S Xu, M Momin, S Ahmed, A Hossain… - Advanced …, 2023 - Wiley Online Library
Optogenetic modulation of brain neural activity that combines optical and electrical modes in
a unitary neural system has recently gained robust momentum. Controlling illumination …

Flexible fiber-based optoelectronics for neural interfaces

S Park, G Loke, Y Fink, P Anikeeva - Chemical Society Reviews, 2019 - pubs.rsc.org
Neurological and psychiatric conditions pose an increasing socioeconomic burden on our
aging society. Our ability to understand and treat these conditions relies on the development …

Nonhuman primate optogenetics: recent advances and future directions

A Galvan, WR Stauffer, L Acker… - Journal of …, 2017 - Soc Neuroscience
Optogenetics is the use of genetically coded, light-gated ion channels or pumps (opsins) for
millisecond resolution control of neural activity. By targeting opsin expression to specific cell …

Design and manufacturing challenges of optogenetic neural interfaces: a review

SB Goncalves, JF Ribeiro, AF Silva… - Journal of neural …, 2017 - iopscience.iop.org
Optogenetics is a relatively new technology to achieve cell-type specific neuromodulation
with millisecond-scale temporal precision. Optogenetic tools are being developed to …

Patterned photostimulation via visible-wavelength photonic probes for deep brain optogenetics

E Segev, J Reimer, LC Moreaux, TM Fowler… - …, 2017 - spiedigitallibrary.org
Optogenetic methods developed over the past decade enable unprecedented optical
activation and silencing of specific neuronal cell types. However, light scattering in neural …

Optrodes for combined optogenetics and electrophysiology in live animals

S Dufour, Y De Koninck - Neurophotonics, 2015 - spiedigitallibrary.org
Optical tissue properties limit visible light depth penetration in tissue. Because of this, the
recent development of optogenetic tools was quickly followed by the development of light …

Compact silicon-based optrode with integrated laser diode chips, SU-8 waveguides and platinum electrodes for optogenetic applications

M Schwaerzle, O Paul, P Ruther - Journal of Micromechanics and …, 2017 - iopscience.iop.org
We report on a compact optrode, ie a MEMS-based, invasive, bidirectional neural interface
allowing to control neural activity using light while neural signals are recorded nearby. The …

Optical fiber tips for biological applications: from light confinement, biosensing to bioparticles manipulation

JS Paiva, PAS Jorge, CC Rosa, JPS Cunha - Biochimica et Biophysica Acta …, 2018 - Elsevier
Background The tip of an optical fiber has been considered an attractive platform in Biology.
The simple cleaved end of an optical fiber can be machined, patterned and/or …

A Multichannel flexible optoelectronic fiber device for distributed implantable neurological stimulation and monitoring

J Yu, W Ling, Y Li, N Ma, Z Wu, R Liang, H Pan, W Liu… - Small, 2021 - Wiley Online Library
Optical fibers made of polymeric materials possess high flexibility that can potentially
integrate with flexible electronic devices to realize complex functions in biology and …

Advanced electrical and optical microsystems for biointerfacing

SN Obaid, Z Chen, L Lu - Advanced Intelligent Systems, 2020 - Wiley Online Library
Electrical and optical biointerfaces have contributed considerably to understanding
biological systems. Recent advances in biocompatible materials, structure designs, and …