Stem cell therapy for spinal cord injury

L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …

[HTML][HTML] MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases

H Zhou, Y He, W Xiong, S Jing, X Duan, Z Huang… - Bioactive materials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

3D bioprinting of neural tissues

M Cadena, L Ning, A King, B Hwang… - Advanced …, 2021 - Wiley Online Library
The human nervous system is a remarkably complex physiological network that is inherently
challenging to study because of obstacles to acquiring primary samples. Animal models …

A critical review on three dimensional-printed chitosan hydrogels for development of tissue engineering

M Sahranavard, A Zamanian, F Ghorbani… - Bioprinting, 2020 - Elsevier
Among different techniques to produce scaffolds, three-dimensional (3D) printing has
attracted a great deal of attention because of a desirable control to generate customized and …

[HTML][HTML] Multiple strategies enhance the efficacy of MSCs transplantation for spinal cord injury

QM Pang, KQ Deng, M Zhang, XC Wu, RL Yang… - Biomedicine & …, 2023 - Elsevier
Spinal cord injury (SCI) is a serious complication of the central nervous system (CNS) after
spine injury, often resulting in severe sensory, motor, and autonomic dysfunction below the …

Sustained delivery of neurotrophic factors to treat spinal cord injury

A Muheremu, L Shu, J Liang, A Aili… - Translational …, 2021 - degruyter.com
Acute spinal cord injury (SCI) is a devastating condition that results in tremendous physical
and psychological harm and a series of socioeconomic problems. Although neurons in the …

Three-dimensional graphene foam as a conductive scaffold for cardiac tissue engineering

S Bahrami, N Baheiraei, M Mohseni… - Journal of …, 2019 - journals.sagepub.com
Myocardial infarction is one of the major causes of mortality throughout the world. Cardiac
scaffolds are tissue-engineered structures for the treatment of myocardial infarction and are …

Generation of insulin‐producing cells from human adipose‐derived mesenchymal stem cells on PVA scaffold by optimized differentiation protocol

SE Enderami, M Soleimani, Y Mortazavi… - Journal of cellular …, 2018 - Wiley Online Library
The studies have been done on patient‐specific human adipose‐derived from mesenchymal
stem cells (hADSCs) like a series of autologous growth factors and nanofibrous scaffolds …

GDNF gene-engineered adipose-derived stem cells seeded Emu oil-loaded electrospun nanofibers for axonal regeneration following spinal cord injury

K Nejati, D Mehdi, S Ghareghomi, E Mostafavi… - Journal of Drug Delivery …, 2020 - Elsevier
Background Spinal cord injury (SCI) activates a cascade of signaling pathways which results
in impaired sensory and motor function without restoration of function due to the very limited …

History of glial cell line-derived neurotrophic factor (GDNF) and its use for spinal cord injury repair

MJ Walker, XM Xu - Brain sciences, 2018 - mdpi.com
Following an initial mechanical insult, traumatic spinal cord injury (SCI) induces a secondary
wave of injury, resulting in a toxic lesion environment inhibitory to axonal regeneration. This …