Alcohol septal ablation in hypertrophic cardiomyopathy: For which patients?

A Achim, AM Serban, SDC Mot, G Leibundgut… - ESC Heart …, 2023 - Wiley Online Library
Percutaneous and surgical therapies for septal reduction for hypertrophic cardiomyopathy
have been going head‐to‐head for the past 20 years with similar outcomes and mortality …

Contemporary therapies and future directions in the management of hypertrophic cardiomyopathy

E Packard, A de Feria, S Peshin, N Reza… - Cardiology and …, 2022 - Springer
Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by pathogenic variants in
sarcomeric genes, leading to left ventricular hypertrophy and complex phenotypic …

Transcatheter myotomy to treat hypertrophic cardiomyopathy and enable transcatheter mitral valve replacement: first-in-human report of septal scoring along the …

AB Greenbaum, JM Khan, CG Bruce… - Circulation …, 2022 - Am Heart Assoc
Transcatheter mitral valve replacement (TMVR) risks left ventricular outflow tract (LVOT)
obstruction from permanent displacement of the anterior leaflet or the implant itself in cases …

A systematic review of present and future pharmaco‐structural therapies for hypertrophic cardiomyopathy

MA Sawan, S Prabakaran, M D'Souza… - Clinical …, 2024 - Wiley Online Library
Hypertrophic cardiomyopathy (HCM) is a common contemporary, treatable, genetic disorder
that can be compatible with normal longevity. While current medical therapies are …

Reshaping the ventricle from within: MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) ventriculoplasty in swine

CG Bruce, JM Khan, T Rogers, DK Yildirim… - Basic to Translational …, 2023 - jacc.org
Summary MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) is a
transcatheter ventricular remodeling procedure. A transvenous tension element is placed …

Unmet needs and future directions in hypertrophic cardiomyopathy

S Kaur, M Desai - Progress in Cardiovascular Diseases, 2023 - Elsevier
Hypertrophic cardiomyopathy (HCM) is a highly treatable monogenetic disorder affecting
nearly 0.2% of the population. The high burden of this disease demands suitable measures …

Transcatheter myotomy to reduce left ventricular outflow obstruction

AB Greenbaum, HA Ueyama, PT Gleason… - Journal of the American …, 2024 - jacc.org
Background Left ventricular outflow tract (LVOT) obstruction is a source of morbidity in
hypertrophic cardiomyopathy (HCM) and a life-threatening complication of transcatheter …

Transcatheter electrosurgery: a narrative review

CG Bruce, JM Khan, T Rogers, DK Yildirim… - Circulation …, 2023 - Am Heart Assoc
Transcatheter electrosurgery describes the ability to cut and traverse tissue, at a distance,
without an open surgical field and is possible using either purpose-built or off-the-shelf …

Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE) Deep Ablation in Inaccessible Targets

RN Halaby, CG Bruce, A Kolandaivelu, NK Bhatia… - Clinical …, 2024 - jacc.org
Background Deep intramural ventricular tachycardia substrate targets are difficult to access,
map, and ablate from endocardial and epicardial surfaces, resulting in high recurrence …

EDEN (Electrocardiographic Radial Depth Navigation) A Novel Approach to Navigate Inside Heart Muscle

CG Bruce, DK Yildirim, A Kolandaivelu, JM Khan… - Clinical …, 2023 - jacc.org
Background Intramyocardial guidewire navigation is a novel technique that allows free
transcatheter movement within ventricular muscle. Guidewire radial depth, between …