Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Vaccines for human schistosomiasis: recent progress, new developments and future prospects

AJ Molehin, DP McManus, H You - International Journal of Molecular …, 2022 - mdpi.com
Schistosomiasis, caused by human trematode blood flukes (schistosomes), remains one of
the most prevalent and serious of the neglected tropical parasitic diseases. Currently …

Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

RCO Sanches, S Tiwari, LCG Ferreira… - Frontiers in …, 2021 - frontiersin.org
Schistosomiasis remains a serious health issue nowadays for an estimated one billion
people in 79 countries around the world. Great efforts have been made to identify good …

Immunoinformatics and molecular docking studies reveal a novel Multi-Epitope peptide vaccine against pneumonia infection

SR Mahapatra, J Dey, T Kaur, R Sarangi, AA Bajoria… - Vaccine, 2021 - Elsevier
Pneumonia is a major endemic disease around the world, and an effective vaccine is the
need of the hour to fight against the disease. When there are no appropriate antiviral and …

Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach

M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …

Structural basis and designing of peptide vaccine using PE-PGRS family protein of Mycobacterium ulcerans—An integrated vaccinomics approach

Z Nain, MM Karim, MK Sen, UK Adhikari - Molecular Immunology, 2020 - Elsevier
Buruli ulcer is an emerging tissue-necrosis infectious disease, caused by the pathogen
Mycobacterium ulcerans, leading to permanent deformity if untreated. Despite this …

Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis

A Rehman, S Ahmad, F Shahid, A Albutti… - Vaccines, 2021 - mdpi.com
Schistosomiasis is a parasitic infection that causes considerable morbidity and mortality in
the world. Infections of parasitic blood flukes, known as schistosomes, cause the disease …

Exploring lassa virus proteome to design a multi-epitope vaccine through immunoinformatics and immune simulation analyses

SB Sayed, Z Nain, MSA Khan, F Abdulla… - International Journal of …, 2020 - Springer
Lassa virus (LASV) is responsible for a type of acute viral haemorrhagic fever referred to as
Lassa fever. Lack of adequate treatment and preventive measures against LASV resulted in …

A multi‐epitope chimeric protein elicited a strong antibody response and partial protection against Edwardsiella ictaluri in Nile tilapia

VI Machimbirike, N Pornputtapong… - Journal of fish …, 2022 - Wiley Online Library
Edwardsiella ictaluri infects several fish species and protection of the all the susceptible fish
hosts from the pathogen using a monovalent vaccine is impossible because the species is …

[HTML][HTML] A designed peptide-based vaccine to combat Brucella melitensis, B. suis and B. abortus: Harnessing an epitope mapping and immunoinformatics approach

H Tarrahimofrad, J Zamani, MR Hamblin… - Biomedicine & …, 2022 - Elsevier
Vaccines against Brucella abortus, B. melitensis and B. suis have been based on weakened
or killed bacteria, however there is no recombinant vaccine for disease prevention or …