[HTML][HTML] Oncolytic ImmunoViroTherapy: A long history of crosstalk between viruses and immune system for cancer treatment

S Feola, S Russo, E Ylösmäki, V Cerullo - Pharmacology & therapeutics, 2022 - Elsevier
Cancer Immunotherapy relies on harnessing a patient's immune system to fine-tune specific
anti-tumor responses and ultimately eradicate cancer. Among diverse therapeutic …

[HTML][HTML] CAR-T cells targeting immune checkpoint pathway players

V Golubovskaya - Frontiers in Bioscience-Landmark, 2022 - imrpress.com
CAR (Chimeric antigen receptor)-T cell therapy has become a very promising type of
immunotherapy against hematological cancers. This report is focused on CAR-T cells …

[HTML][HTML] From barriers to novel strategies: Smarter CAR T therapy hits hard to tumors

MB Khawar, F Ge, A Afzal, H Sun - Frontiers in Immunology, 2023 - frontiersin.org
Chimeric antigen receptor (CAR) T cell therapy for solid tumors shows promise, but several
hurdles remain. Strategies to overcome barriers such as CAR T therapy-related toxicities …

[HTML][HTML] Application and design of switches used in CAR

P Głowacki, P Rieske - Cells, 2022 - mdpi.com
Among the many oncology therapies, few have generated as much excitement as CAR-T.
The success of CAR therapy would not have been possible without the many discoveries …

[PDF][PDF] Engineering chimeric autoantibody receptor T cells for targeted B cell depletion in multiple sclerosis model: An in-vitro study

M Sahlolbei, M Azangou-Khyavy, J Khanali… - Heliyon, 2023 - cell.com
Background Recent evidence suggests that B cells and autoantibodies have a substantial
role in the pathogenesis of Multiple sclerosis. T cells could be engineered to express …

[HTML][HTML] The Contribution of the Minimal Promoter Element to the Activity of Synthetic Promoters Mediating CAR Expression in the Tumor Microenvironment

Y Greenshpan, O Sharabi, KM Yegodayev… - International Journal of …, 2022 - mdpi.com
Harnessing immune effector cells to benefit cancer patients is becoming more and more
prevalent in recent years. However, the increasing number of different therapeutic …

Mesenchymal stromal cells and CAR‐T cells in regenerative medicine: The homing procedure and their effective parameters

H Kolahi Azar, A Imanpour, H Rezaee… - European Journal of …, 2024 - Wiley Online Library
Mesenchymal stromal cells (MSCs) and chimeric antigen receptor (CAR)‐T cells are two
core elements in cell therapy procedures. MSCs have significant immunomodulatory effects …

[HTML][HTML] Mini review: Advances and challenges in CAR-T cell therapy: from early chimeric antigen receptors to future frontiers in oncology

C Ceballos, MC Viguria, C Panizo… - Frontiers in …, 2023 - frontiersin.org
Cell therapy utilizing chimeric antigen receptors (CARs) in conjunction with immune cells,
primarily T lymphocytes, is known as CAR-T cell therapy. This innovative approach is …

[PDF][PDF] Synthetische Rezeptorbiologie als Werkzeug zur Erforschung von Zytokin-und Wachstumsfaktorrezeptoren Entwicklung synthetischer IL-22R, IL-27R, IL-39R …

M Kuchner - 2023 - docserv.uni-duesseldorf.de
Synthetische Rezeptorbiologie als Werkzeug zur Erforschung von Zytokin- und
Wachstumsfaktorrezeptoren Entwicklung synthetischer Page 1 Aus dem Institut für …