Multiple roles for neutrophils in atherosclerosis

O Soehnlein - Circulation research, 2012 - Am Heart Assoc
Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

Biological activities of HDL subpopulations and their relevance to cardiovascular disease

L Camont, MJ Chapman, A Kontush - Trends in molecular medicine, 2011 - cell.com
The concept of raising high-density lipoprotein (HDL) has been the focus of increasing
attention as a strategy to reduce cardiovascular disease. HDL particles are, however, highly …

High-density lipoprotein anti-inflammatory capacity and incident cardiovascular events

C Jia, JLC Anderson, EG Gruppen, Y Lei, SJL Bakker… - Circulation, 2021 - Am Heart Assoc
Background: The role of high-density lipoprotein (HDL) function in cardiovascular disease
represents an important emerging concept. The present study investigated whether HDL anti …

HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells

F Tabet, KC Vickers, LF Cuesta Torres… - Nature …, 2014 - nature.com
High-density lipoproteins (HDL) have many biological functions, including reducing
endothelial activation and adhesion molecule expression. We recently reported that HDL …

Association between systemic immune-inflammation index and metabolic syndrome and its components: Results from the National Health and Nutrition Examination …

Y Zhao, W Shao, Q Zhu, R Zhang, T Sun… - Journal of translational …, 2023 - Springer
Abstract Background Metabolic syndrome (MetS), a worldwide public health problem, affects
human health and quality of life in a dramatic manner. A growing evidence base suggests …

Cardiovascular disease risk reduction by raising HDL cholesterol–current therapies and future opportunities

KM Ali, A Wonnerth, K Huber… - British journal of …, 2012 - Wiley Online Library
Since the first discovery of an inverse correlation between high‐density lipoprotein‐
cholesterol (HDL‐C) levels and coronary heart disease in the 1950s the life cycle of HDL, its …

Cardioprotective functions of HDLs1

KA Rye, PJ Barter - Journal of lipid research, 2014 - ASBMB
Multiple human population studies have established the concentration of high density
lipoprotein (HDL) cholesterol as an independent, inverse predictor of the risk of having a …

High-density lipoprotein reduces the human monocyte inflammatory response

AJ Murphy, KJ Woollard, A Hoang… - … , and vascular biology, 2008 - Am Heart Assoc
Objective—Whereas the anti–inflammatory effects of high-density lipoprotein (HDL) on
endothelial cells are well described, such effects on monocytes are less studied. Methods …

High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target

TF Lüscher, U Landmesser, A von Eckardstein… - Circulation …, 2014 - Am Heart Assoc
High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with
many minor proteins and lipids that influence the function of HDL. Although HDL is a …

Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin …

SA Sorrentino, C Besler, L Rohrer, M Meyer… - Circulation, 2010 - Am Heart Assoc
Background—High-density lipoprotein (HDL)–raising therapies are currently under intense
evaluation, but the effects of HDL may be highly heterogeneous. We therefore compared the …