The development and function of the central nervous system rely on the microtubule (MT)
and actin cytoskeletons and their respective effectors. Although the structural role of the …

The large number of transgenic mice realized thus far with different purposes allows
addressing new questions, such as which animals, over the entire set of transgenic animals …

Introduction Recent studies have suggested that schizophrenia is associated with alterations
in the synaptic connectivity involving cytoskeletal proteins. The microtubule-associated …

Abstract Background: STOP/MAP6 null (KO) mice recapitulate behavioral abnormalities
related to positive and negative symptoms and cognitive deficits of schizophrenia. Here, we …

Background The skeletal muscle fiber has a specific and precise intracellular organization
which is at the basis of an efficient muscle contraction. Microtubules are long known to play …

J. Neurochem.(2012) 121, 99–114. Abstract The microtubule‐associated Stable Tubulie
Only Polypeptide (STOP; also known as MAP6) protein plays a key role in neuron …

Recent evidence underlines the crucial role of neuronal cytoskeleton in the pathophysiology
of psychiatric diseases. In this line, the deletion of STOP/MAP 6 (Stable Tubule Only …

Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of
genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of …

Recently evidence has accumulated that schizophrenia can arise from primary synaptic
defects involving structural proteins particularly, microtubule associated proteins. Previous …

J. Neurochem.(2010) 115, 1579–1594. Abstract The deletion of microtubule‐associated
protein stable tubule only polypeptide (STOP) leads to neuroanatomical, biochemical and …