Clinical and biological insights from viral genome sequencing
Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not
only for basic research but also for clinical science and practice. In virology, WGS is …
only for basic research but also for clinical science and practice. In virology, WGS is …
Deep sequencing: becoming a critical tool in clinical virology
ME Quiñones-Mateu, S Avila, G Reyes-Teran… - Journal of clinical …, 2014 - Elsevier
Population (Sanger) sequencing has been the standard method in basic and clinical DNA
sequencing for almost 40 years; however, next-generation (deep) sequencing …
sequencing for almost 40 years; however, next-generation (deep) sequencing …
Human immunodeficiency virus drug resistance: 2018 recommendations of the International Antiviral Society–USA Panel
HF Günthard, V Calvez, R Paredes… - Clinical Infectious …, 2019 - academic.oup.com
Background Contemporary antiretroviral therapies (ART) and management strategies have
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …
Human immunodeficiency virus immune cell receptors, coreceptors, and cofactors: implications for prevention and treatment
In the last three decades, extensive research on human immunodeficiency virus (HIV) has
highlighted its capability to exploit a variety of strategies to enter and infect immune cells …
highlighted its capability to exploit a variety of strategies to enter and infect immune cells …
Sensitive deep-sequencing-based HIV-1 genotyping assay to simultaneously determine susceptibility to protease, reverse transcriptase, integrase, and maturation …
With 29 individual antiretroviral drugs available from six classes that are approved for the
treatment of HIV-1 infection, a combination of different phenotypic and genotypic tests is …
treatment of HIV-1 infection, a combination of different phenotypic and genotypic tests is …
SARS-CoV-2 genomics and impact on clinical care for COVID-19
R Lorenzo-Redondo… - Journal of …, 2023 - academic.oup.com
The emergence and worldwide spread of SARS-CoV-2 during the COVID-19 pandemic
necessitated the adaptation and rapid deployment of viral WGS and analysis techniques that …
necessitated the adaptation and rapid deployment of viral WGS and analysis techniques that …
Deep sequencing for HIV-1 clinical management
M Casadellà, R Paredes - Virus research, 2017 - Elsevier
The emerging HIV-1 resistance epidemic is threatening the impressive global advances in
HIV-1 infection treatment and prevention achieved in the last decade. Next-generation …
HIV-1 infection treatment and prevention achieved in the last decade. Next-generation …
Next-generation sequencing in veterinary medicine: how can the massive amount of information arising from high-throughput technologies improve diagnosis, control …
The development of high-throughput molecular technologies and associated bioinformatics
has dramatically changed the capacities of scientists to produce, handle, and analyze large …
has dramatically changed the capacities of scientists to produce, handle, and analyze large …
A pan-HIV strategy for complete genome sequencing
MG Berg, J Yamaguchi… - Journal of clinical …, 2016 - Am Soc Microbiol
Molecular surveillance is essential to monitor HIV diversity and track emerging strains. We
have developed a universal library preparation method (HIV-SMART [ie, s witching m …
have developed a universal library preparation method (HIV-SMART [ie, s witching m …
Next-generation sequencing to help monitor patients infected with HIV: ready for clinical use?
RM Gibson, CL Schmotzer… - Current infectious disease …, 2014 - Springer
Given the extreme variability of the human immunodeficiency virus (HIV) and its ability to
replicate as complex viral populations, HIV variants with reduced susceptibility to …
replicate as complex viral populations, HIV variants with reduced susceptibility to …