Addressing big data challenges in mass spectrometry-based metabolomics

J Guo, H Yu, S Xing, T Huan - Chemical Communications, 2022 - pubs.rsc.org
Advancements in computer science and software engineering have greatly facilitated mass
spectrometry (MS)-based untargeted metabolomics. Nowadays, gigabytes of metabolomics …

Quantitative challenges and their bioinformatic solutions in mass spectrometry-based metabolomics

H Yu, B Low, Z Zhang, J Guo, T Huan - TrAC Trends in Analytical …, 2023 - Elsevier
Improving the quantitative performance of mass spectrometry (MS)-based metabolomics is
the key to its successful application in a broad range of research questions. Like other …

AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications

LM Petrick, N Shomron - Cell Reports Physical Science, 2022 - cell.com
Metabolomics describes a high-throughput approach for measuring a repertoire of
metabolites and small molecules in biological samples. One utility of untargeted …

[PDF][PDF] Managerial Competence and Inventory Management in SME Financial Performance: A Hungarian Perspective

A Ramadan, D Alkhodary… - Journal of Statistics …, 2024 - naturalspublishing.com
This study examines how managerial skills and inventory management affect the financial
performance of SMEs in Hungary's Business Products and Services sector. It employs a …

Characterization of Hair Metabolome in 5xFAD Mice and Patients with Alzheimer's Disease Using Mass Spectrometry-Based Metabolomics

CW Chang, JY Hsu, YT Lo, YH Liu… - ACS Chemical …, 2024 - ACS Publications
Hair emerged as a biospecimen for long-term investigation of endogenous metabolic
perturbations, reflecting the chemical composition circulating in the blood over the past …

Reducing Quantitative Uncertainty Caused by Data Processing in Untargeted Metabolomics

Z Zhang, H Yu, E Wong-Ma, P Dokouhaki… - Analytical …, 2024 - ACS Publications
Processing liquid chromatography–mass spectrometry-based metabolomics data using
computational programs often introduces additional quantitative uncertainty, termed …

An anchored experimental design and meta-analysis approach to address batch effects in large-scale metabolomics

AO Shaver, BM Garcia, GJ Gouveia… - Frontiers in Molecular …, 2022 - frontiersin.org
Untargeted metabolomics studies are unbiased but identifying the same feature across
studies is complicated by environmental variation, batch effects, and instrument variability …

Bulk synthesis of conductive non-metallic carbon nanospheres and a 3D printed carrier device for scanning electron microscope calibration

ML Wang, JC Wu, LY Hao, Q Wei - RSC advances, 2023 - pubs.rsc.org
Herein, a facile method is proposed for the bulk synthesis of conductive non-metallic carbon
nanospheres with controllable morphology to replace conventional metal calibration …

Development of bioinformatic solution to enhance metabolomics data quality and its application in plant research

Z Zhang - 2023 - open.library.ubc.ca
This thesis delves into the development and application of metabolomics, a discipline
focused on the comprehensive study of metabolites within biological systems. The research …

Development of analytical workflows and bioinformatic programs for mass spectrometry-based metabolomics

H Yu - 2023 - open.library.ubc.ca
Quantitative determination of metabolite concentrations in biological samples is fundamental
to biological and clinical research. Metabolomics analyzes the entire set of metabolites in a …