Measurement of cardiac troponins

PO Collinson, FG Boa, DC Gaze - Annals of clinical …, 2001 - journals.sagepub.com
The cardiac troponins form part of the regulatory mechanism for muscle contraction. Specific
cardiac isoforms of cardiac troponin T and cardiac troponin I exist and commercially …

Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock

KM ver Elst, HD Spapen, DN Nguyen… - Clinical …, 2000 - academic.oup.com
Background: Cardiac depression in severe sepsis and septic shock is characterized by left
ventricular (LV) failure. To date, it is unclear whether clinically unrecognized myocardial cell …

Review of the effect of intravenous lipid emulsion on laboratory analyses

AM Grunbaum, BM Gilfix, RS Hoffman… - Clinical …, 2016 - Taylor & Francis
Context Although the clinical use of intravenous lipid emulsion therapy for the treatment of
lipophilic drug toxicity is increasing, the focus of most publications is on outcome in …

Cardiac troponins as indicators of acute myocardial damage in dogs

IA Burgener, AI Kovacevic, GN Mauldin… - Journal of veterinary …, 2006 - Wiley Online Library
Cardiac troponin I (cTnI) and T (cTnT) have a high sequence homology across phyla and
are sensitive and specific markers of myocardial damage. The purpose of this study was to …

The impact of hemolysis on Ortho-Clinical Diagnostic's ECi and Roche's elecsys immunoassay systems

JA Snyder, MW Rogers, MS King, JC Phillips… - Clinica chimica acta, 2004 - Elsevier
Background: Hemolysis is regularly encountered in clinical specimens and often interferes
with a variety of laboratory test methods. Although not widely recognized, immunoassays …

Present issues in the determination of troponins and other markers of cardiac damage

M Panteghini - Clinical Biochemistry, 2000 - Elsevier
Objective: To review some of the recently proposed improvements and the corresponding
apparent issues in the field of biochemical markers of cardiac damage. Conclusions: The …

Biochemical markers of cardiac damage: from efficiency to effectiveness

M Plebani - Clinica Chimica Acta, 2001 - Elsevier
Testing for the diagnosis of acute myocardial infarction and other diseases included in the
spectrum of the so-called “acute coronary syndrome” is rapidly changing from the traditional …

Issues in the development of hemoglobin based oxygen carriers

TN Estep - Seminars in Hematology, 2019 - Elsevier
Hemoglobin based oxygen carriers (HBOCs) have been developed as alternative oxygen
transporting formulations for the acute treatment of anemia and ischemia. Efficacy has been …

New generation cardiac troponin I assay for the access immunoassay system

P Venge, B Lindahl, L Wallentin - Clinical chemistry, 2001 - academic.oup.com
reaction volume of 10 L with 0.5 M each of the primers 5-AGCACCAAGCAATATCATTTATG-
3 and 5-GC-CTCCAAGTATCTGCACAG-3, 50 ng of geno reaction volume of 10 L with 0.5 M …

Negative interference of bilirubin and hemoglobin in the MEIA troponin I assay but not in the MEIA CK‐MB assay

A Dasgupta, A Wells, DA Biddle - Journal of Clinical Laboratory …, 2001 - Wiley Online Library
Troponin I is a sensitive and specific marker for the diagnosis of myocardial infarction.
Several commercially available immunoassays measure the concentration of troponin I in …