The asymmetric cell division of stem cells, which produces one stem cell and one
differentiating cell, has emerged as a mechanism to balance stem cell self-renewal and …

Asymmetric cell division gives rise to two daughter cells that inherit different determinants,
thereby acquiring different fates. Polarized trafficking of endosomes containing fate …

Protein phosphatase 1 (PP1) is expressed in all eukaryotic cells and catalyzes a sizable
fraction of protein Ser/Thr dephosphorylation events. It is tightly regulated in space and time …

Symmetric and asymmetric cell divisions are conserved strategies for stem cell expansion
and the generation of more committed progeny, respectively. Here, we demonstrate that in …

The phenomenal diversity of neuronal types in the central nervous system is achieved in
part by the asymmetric division of neural precursors. In zebrafish neural precursors …

Genomic regions that play a role in parasite defense are often found to be highly variable,
with the major histocompatibility complex serving as an iconic example. Single nucleotide …

Asymmetric localization and translation of mRNAs is used by single cells to sense their
environment and integrate extrinsic cues with the appropriate cellular response. Here we …

Traditionally, we imagine that cell division gives rise to two identical daughter cells.
Nevertheless, all cell divisions, to some degree, display asymmetry. Asymmetric cell division …

The asymmetric cell division determines cell diversity and distinct sibling cell fates by
mechanisms linked to mitosis. Many adult stem cells divide asymmetrically to balance self …

Cytokinesis is the final step of cell division following chromosome segregation that
generates two daughter cells. The conserved exocyst complex is required for scission of the …