Zebrafish: a convenient tool for myelopoiesis research

YX Hu, Q Jing - Cell Regeneration, 2023 - Springer
Myelopoiesis is the process in which the mature myeloid cells, including monocytes/
macrophages and granulocytes, are developed. Irregular myelopoiesis may cause and …

A robust pipeline for efficient knock-in of point mutations and epitope tags in zebrafish using fluorescent PCR based screening

B Carrington, R Ramanagoudr-Bhojappa, E Bresciani… - BMC genomics, 2022 - Springer
Background Genome editing using CRISPR/Cas9 has become a powerful tool in zebrafish
to generate targeted gene knockouts models. However, its use for targeted knock-in remains …

Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency

CB Mahony, L Copper, P Vrljicak, B Noyvert… - Cell Reports, 2023 - cell.com
Inherited bone marrow failure associated with heterozygous mutations in GATA2
predisposes toward hematological malignancies, but the mechanisms remain poorly …

Congenital asplenia impairs heme-iron recycling during erythropoiesis in zebrafish

L Xie, Y Tao, Z Shen, H Deng, X Duan, Y Xue… - Developmental & …, 2024 - Elsevier
The spleen is postulated to be a hematopoietic tissue in adult fish; however, clear evidence
is still lacking to define its role in hematopoietic activity. In our previous study, a congenitally …

Gata2a Mutation Causes Progressive Microphthalmia and Blindness in Nile Tilapia

X Liu, L Zhou, W Li, J Wu, D Wang - International Journal of Molecular …, 2023 - mdpi.com
The normal development of lens fiber cells plays a critical role in lens morphogenesis and
maintaining transparency. Factors involved in the development of lens fiber cells are largely …