Cancer cachexia is a devastating, multifactorial and often irreversible syndrome that affects
around 50–80% of cancer patients, depending on the tumour type, and that leads to …

Up to 50% of cancer patients suffer from a progressive atrophy of adipose tissue and
skeletal muscle, called cachexia, resulting in weight loss, a reduced quality of life, and a …

The importance of β-adrenergic signaling in the heart has been well documented, but it is
only more recently that we have begun to understand the importance of this signaling …

The maintenance of muscle mass is critical for health and issues associated with the quality
of life. Over the last decade, extensive progress has been made with regard to our …

Dietary proteins/essential amino acids (EAAs) are nutrients with anabolic properties that
may increase muscle mass or attenuate muscle loss during immobilization and aging via the …

Cancer cachexia is a multifactorial syndrome that develops during malignant tumor growth.
Changes in plasma levels of several hormones and inflammatory factors result in an intense …

Muscle cachexia has a major detrimental impact on cancer patients, being responsible for
30% of all cancer deaths. It is characterized by a debilitating loss in muscle mass and …

Cachexia is frequently accompanied by severe metabolic derangements, although the
mechanisms responsible for this debilitating condition remain unclear. Pyruvate …

Cancer-induced cachexia has a negative impact on quality of life and adversely affects
therapeutic outcomes and survival rates. It is characterized by, often severe, loss of muscle …

Approximately half of all cancer patients present with cachexia, a condition in which disease-
associated metabolic changes lead to a severe loss of skeletal muscle mass. Working …